Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3971345 | 0.83 | HPGD (0.43) | KDM4EALDH1A1SMN1; SMN2MAPTPOLB | |
| SCHEMBL27607614 | 0.76 | MAPT (0.35) | LMNAKDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL3166465 | 0.72 | PTGS1 (0.37) | LMNATSHRPTGS2 | |
| SCHEMBL9147377 | 0.66 | AKR1B1 (0.32) | ALDH1A1MAPTMAPK1RAB9A | |
| SCHEMBL3903122 | 0.64 | CA1 (0.53) | KDM4EMAPTPOLB | |
| Naphthalene SCHEMBL31244560 | 0.64 | HCAR2 (0.37) | LMNAKDM4ETSHRMAPTMAPK1 | |
| SCHEMBL24802650 | 0.63 | NPC1 (0.40) | LMNAALDH1A1SMN1; SMN2MAPTRAB9A | |
| SCHEMBL1986826 | 0.63 | ALOX15 (0.44) | LMNAKDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL3520901 | 0.63 | POLB (0.47) | LMNATSHRSMN1; SMN2MAPTTP53 | |
| Hydrochloric Acid SCHEMBL10335958 | 0.62 | ALOX15 (0.43) | LMNAKDM4EALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1251128-B1 | Cyclohexylamine derivatives as subtype selective N-methyl-D-aspartate antagonists | WARNER LAMBERT CO (US) | 2006-12-06 | — | — | EP | disclosed |
| US-6828341-B2 | Brain disorders; anticonvulsants; central nervous system disorders; psychological disorders | WARNER-LAMBERT COMPANY | 2004-12-07 | — | — | US | disclosed |
| US-20030004212-A1 | Cyclohexylamine derivatives as subtype selective N-Methyl-D-Aspartate antagonists | DEORAZIO RUSSELL JOSEPH (US) | 2003-01-02 | — | — | US | disclosed |
| EP-1251128-A1 | Cyclohexylamine derivatives as subtype selective N-methyl-D-aspartate antagonists | WARNER-LAMBERT COMPANY (US) | 2002-10-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030004212-A1 | Cyclohexylamine derivatives as subtype selective N-Methyl-D-Aspartate antagonists | GLRB, GRIN1, GRIN2B | LMNA 3322/4885KDM4E 1341/4885ALDH1A1 1057/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.