Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | PRKCA | P17252 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | GALR3 | O60755 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6879893 | 0.83 | TSHR (0.46) | TSHRPRKCACHRM2CHRM4CHRM1 | |
| SCHEMBL7606470 | 0.74 | TSHR (0.46) | TSHRPRKCACHRM2CHRM4CHRM1 | |
| SCHEMBL5986991 | 0.74 | TSHR (0.46) | TSHRPRKCACHRM2CHRM4CHRM1 | |
| SCHEMBL5986707 | 0.74 | TSHR (0.46) | TSHRPRKCACHRM2CHRM4CHRM1 | |
| SCHEMBL16077780 | 0.73 | TSHR (0.41) | TSHRPRKCACHRM2CHRM4CHRM1 | |
| SCHEMBL1439919 | 0.73 | PRKCA (0.42) | TSHRPRKCA | |
| SCHEMBL4735899 | 0.73 | PRKCA (0.42) | TSHRPRKCA | |
| SCHEMBL5988357 | 0.71 | TSHR (0.42) | TSHRPRKCACHRM2CHRM4CHRM1 | |
| SCHEMBL7606479 | 0.71 | TSHR (0.42) | TSHRPRKCACHRM2CHRM4CHRM1 | |
| SCHEMBL5987688 | 0.71 | TSHR (0.42) | TSHRPRKCACHRM2CHRM4CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1560488-A4 | ANTIBACTERIAL AGENTS | SMITHKLINE BEECHAM CORP (US) | 2006-08-02 | — | — | EP | disclosed |
| EP-1560488-A2 | ANTIBACTERIAL AGENTS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-08-10 | — | — | EP | disclosed |
| WO-2004041210-A2 | ANTIBACTERIAL AGENTS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-05-21 | — | — | WO | disclosed |
| EP-0966472-A1 | CEPHALOSPORIN DERIVATIVES | Bristol-Myers Squibb Company (US) | 1999-12-29 | — | — | EP | disclosed |
| EP-0966472-A4 | — | — | 1999-12-29 | — | — | EP | disclosed |
| WO-1998023621-A1 | CEPHALOSPORIN DERIVATIVES | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-06-04 | — | — | WO | disclosed |