Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7311596 | 0.81 | AVPR1A (0.66) | AVPR1AAVPR2 | |
| SCHEMBL7320305 | 0.79 | AVPR1A (0.66) | AVPR1AAVPR2 | |
| SCHEMBL5739804 | 0.79 | AVPR1A (0.66) | AVPR1AAVPR2 | |
| SCHEMBL5738984 | 0.79 | AVPR1A (0.66) | AVPR1AAVPR2 | |
| SCHEMBL5118219 | 0.78 | AVPR1A (0.68) | AVPR1AAVPR2 | |
| SCHEMBL4146951 | 0.77 | AVPR1A (0.73) | AVPR1AAVPR2 | |
| SCHEMBL13403212 | 0.74 | AVPR1A (0.85) | AVPR1AAVPR2 | |
| SCHEMBL5739919 | 0.74 | AVPR1A (0.54) | AVPR1AAVPR2 | |
| SCHEMBL8944367 | 0.74 | AVPR2 (0.62) | AVPR1AAVPR2 | |
| SCHEMBL7332293 | 0.73 | AVPR1A (0.83) | AVPR1AAVPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0804438-B1 | TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS | WYETH CORP (US) | 2006-03-15 | — | — | EP | disclosed |
| US-5612334-A | Tricyclic benzazepine vasopressin antagonists | AMERICAN CYANAMID COMPANY (US) | 1997-03-18 | — | — | US | disclosed |
| US-5610156-A | USED IN TREATING DISEASES CHARACTERIZED BY EXCESS RENAL REABSORPTION OF WATER | AMERICAN CYANAMID COMPANY (US) | 1997-03-11 | — | — | US | disclosed |
| WO-1996022293-A1 | TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS | AMERICAN CYANAMID COMPANY (US) | 1996-07-25 | — | — | WO | disclosed |
| US-5536718-A | Tricyclic benzazepine vasopressin antagonists | AMERICAN CYANAMID COMPANY (US) | 1996-07-16 | — | — | US | disclosed |