Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6631147 | 0.87 | AVPR1A (0.54) | AVPR1AAVPR2 | |
| SCHEMBL5628979 | 0.86 | AVPR1A (0.53) | AVPR1AAVPR2 | |
| SCHEMBL5628982 | 0.86 | AVPR1A (0.50) | AVPR1AAVPR2 | |
| SCHEMBL5627248 | 0.84 | AVPR1A (0.48) | AVPR1AAVPR2 | |
| SCHEMBL13403212 | 0.83 | AVPR1A (0.85) | AVPR1AAVPR2 | |
| SCHEMBL5124926 | 0.83 | AVPR1A (0.47) | AVPR1AAVPR2 | |
| SCHEMBL7332293 | 0.82 | AVPR1A (0.83) | AVPR1AAVPR2 | |
| SCHEMBL8944367 | 0.82 | AVPR2 (0.62) | AVPR1AAVPR2 | |
| SCHEMBL6068819 | 0.81 | AVPR1A (0.77) | AVPR1AAVPR2 | |
| SCHEMBL6624843 | 0.81 | AVPR1A (0.77) | AVPR1AAVPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7329653-B2 | Cyclohexylphenyl vasopressin agonists | WYETH (US) | 2008-02-12 | — | — | US | claimed |
| EP-1381608-B1 | CYCLOHEXYLPHENYL VASOPRESSIN AGONISTS | WYETH CORP (US) | 2007-10-10 | — | — | EP | claimed |
| US-20020198191-A1 | Medicine for inducing temporary delay of urination or treatment of disorders of diabetes insipidus, nocturnal enuresis, nocturia, urinary incontinence, or bleeding and coagulation disorders | WYETH (US) | 2002-12-26 | — | — | US | claimed |
| US-7329653-B2 | Cyclohexylphenyl vasopressin agonists | WYETH (US) | 2008-02-12 | — | — | US | disclosed |
| US-7329653-B2 | Cyclohexylphenyl vasopressin agonists | WYETH (US) | 2008-02-12 | — | — | US | disclosed |
| US-7202239-B2 | Cyclohexylphenyl carboxamides tocolytic oxytocin receptor antagonists | WYETH (US) | 2007-04-10 | — | — | US | disclosed |
| US-20060183734-A1 | Cyclohexylphenyl vasopressin agonists | WYETH (US) | 2006-08-17 | — | — | US | disclosed |
| US-7053083-B2 | Cyclohexylphenyl vasopressin agonists | WYETH (US) | 2006-05-30 | — | — | US | disclosed |
| EP-1377582-A1 | NOVEL 3-C(O)R SUBSTITUTED 10-CYCLOHEXYLBENZOYL PYRROLOBENZODIAZEPINES; TOCOLYTIC OXYTOCIN RECEPTOR ANTAGONISTS | Wyeth (US) | 2004-01-07 | — | — | EP | disclosed |
| US-20030027815-A1 | Novel cyclohexylphenyl carboxamides tocolytic oxytocin receptor antagonists | WYETH | 2003-02-06 | — | — | US | disclosed |
| US-20020198191-A1 | Medicine for inducing temporary delay of urination or treatment of disorders of diabetes insipidus, nocturnal enuresis, nocturia, urinary incontinence, or bleeding and coagulation disorders | WYETH (US) | 2002-12-26 | — | — | US | disclosed |
| WO-2002085907-A1 | NOVEL 3-C(O)R SUBSTITUTED 10-CYCLOHEXYLBENZOYL PYRROLOBENZODIAZEPINES; TOCOLYTIC OXYTOCIN RECEPTOR ANTAGONISTS | WYETH (US) | 2002-10-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030027815-A1 | Novel cyclohexylphenyl carboxamides tocolytic oxytocin receptor antagonists | OXTR, OPRL1, CRHR2 | AVPR1A 41/4885AVPR2 49/4885 |
| US-20020198191-A1 | Medicine for inducing temporary delay of urination or treatment of disorders of diabetes insipidus, nocturnal enuresis, nocturia, urinary incontinence, or bleeding and coagulation disorders | F2, AVPR2, SHBG | AVPR1A 6/4885AVPR2 2/4885 |
| US-20060183734-A1 | Cyclohexylphenyl vasopressin agonists | AVPR2, AVPR1A, AVPR1B | AVPR1A 2/4885AVPR2 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.