Ether

Ether

SCHEMBL5738680

CCCC.CCCC.CCOCC

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.41
TSHR P16473 2/20 0.32
THRB P10828 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ether SCHEMBL17491666 1.00 ALDH1A1 (0.41) ALDH1A1TSHRTHRBLMNA
Ether SCHEMBL7426333 1.00 ALDH1A1 (0.41) ALDH1A1TSHRTHRBLMNA
Ether SCHEMBL16111404 1.00 ALDH1A1 (0.41) ALDH1A1TSHRTHRBLMNA
Ether SCHEMBL2785286 1.00 ALDH1A1 (0.41) ALDH1A1TSHRTHRBLMNA
Ether SCHEMBL641155 1.00
Ether SCHEMBL7600629 1.00 ALDH1A1 (0.41) ALDH1A1TSHRTHRBLMNA
Ether SCHEMBL5740091 1.00 ALDH1A1 (0.41) ALDH1A1TSHRTHRBLMNA
Ether SCHEMBL7076838 1.00 ALDH1A1 (0.41) ALDH1A1TSHRTHRBLMNA
Ether SCHEMBL2639432 0.95 ALDH1A1 (0.39) ALDH1A1TSHR
Ether SCHEMBL8708261 0.91 ALDH1A1 (0.37) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3214088-B1 METHOD FOR PRODUCING EUSHEARILIDES UNIV TOKYO SCIENCE FOUND (JP) 2020-02-26 EP disclosed
EP-3214088-A1 METHOD FOR PRODUCING EUSHEARILIDES Tokyo University of Science Foundation (JP) 2017-09-06 EP disclosed
EP-1694638-A1 N-SUBSTITUTED-N-SULFONYLAMINOCYCLOPROPANE COMPOUNDS AND PHARMACEUTICAL USE THEREOF Japan Tobacco, Inc. (JP) 2006-08-30 EP disclosed
WO-2005113509-A1 NOVEL 4-OXOQUINOLINE COMPOUND AND USE THEREOF AS HIV INTEGRASE INHIBITOR JAPAN TOBACCO INC. (JP) 2005-12-01 WO disclosed
WO-2005058808-A1 N-SUBSTITUTED-N-SULFONYLAMINOCYCLOPROPANE COMPOUNDS AND PHARMACEUTICAL USE THEREOF JAPAN TOBACCO INC. (JP) 2005-06-30 WO disclosed
WO-2003103653-A1 METHODS OF TREATING ALZHEIMER'S DISEASE USING ARYL ALKANOIC ACID AMIDES ELAN PHARMACEUTICALS, INC. (US) 2003-12-18 WO disclosed
EP-0882051-A1 THIOPHENOPYRIMIDINES JANSSEN PHARMACEUTICA N.V. (BE) 1998-12-09 EP disclosed
WO-1997029110-A1 THIOPHENOPYRIMIDINES JANSSEN PHARMACEUTICA N.V. (BE) 1997-08-14 WO disclosed