Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 4/20 | 0.32 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8634225 | 0.96 | LMNA (0.41) | LMNACA1CYP3A4L3MBTL1MAPT | |
| SCHEMBL3040106 | 0.94 | CYP3A4 (0.41) | LMNACA1CA12CA2CA7 | |
| SCHEMBL7209537 | 0.94 | LMNA (0.45) | LMNACYP3A4L3MBTL1MAPTPRSS1 | |
| SCHEMBL7204580 | 0.94 | LMNA (0.45) | LMNACYP3A4L3MBTL1MAPTPRSS1 | |
| SCHEMBL7205358 | 0.94 | LMNA (0.45) | LMNACYP3A4L3MBTL1MAPTPRSS1 | |
| SCHEMBL22342662 | 0.89 | CA12 (0.45) | CA1CA12CA2CA7CA14 | |
| SCHEMBL3030454 | 0.88 | CYP3A4 (0.48) | LMNACA2CYP3A4L3MBTL1PRSS1 | |
| SCHEMBL10527246 | 0.88 | PRSS1 (0.42) | LMNACA2CYP3A4L3MBTL1MAPT | |
| SCHEMBL1110039 | 0.86 | CYP3A4 (0.47) | LMNACA2CYP3A4L3MBTL1MAPT | |
| SCHEMBL96307 | 0.82 | CYP3A4 (0.55) | LMNACA2CYP3A4L3MBTL1PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636192-A1 | 3-ALKYLIDENEHYDRAZINO SUBSTITUTED HETEROARYL COMPOUNDS AS THROMBOPOIETIN RECEPTOR ACTIVATORS | Nissan Chemical Industries, Ltd. (JP) | 2006-03-22 | — | — | EP | disclosed |
| WO-2004108683-A1 | 3-ALKYLIDENEHYDRAZINO SUBSTITUTED HETEROARYL COMPOUNDS AS THROMBOPOIETIN RECEPTOR ACTIVATORS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2004-12-16 | — | — | WO | disclosed |