Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRG | P62508 | 6/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5738665 | 0.90 | CA1 (0.43) | ESRRGKMT2AMEN1GAAMAPT | |
| SCHEMBL5738808 | 0.88 | ESRRG (0.41) | ESRRGNR1H4EPHX2KMT2AALOX5 | |
| SCHEMBL5739305 | 0.88 | NR1H4 (0.46) | ESRRGNR1H4EPHX2KMT2AMEN1 | |
| SCHEMBL5739289 | 0.88 | ESRRG (0.35) | ESRRGGAAALOX5PTGS2SPHK2 | |
| SCHEMBL5738282 | 0.83 | ESRRG (0.40) | ESRRGNR1H4EPHX2KMT2AMEN1 | |
| SCHEMBL5737439 | 0.83 | ESRRG (0.40) | ESRRGKMT2AMEN1GAAMAPT | |
| SCHEMBL5738615 | 0.83 | ESRRG (0.40) | ESRRGNR1H4EPHX2KMT2AMEN1 | |
| SCHEMBL5738456 | 0.82 | SPHK2 (0.34) | ESRRGHPGDCA1CA2ALOX5 | |
| SCHEMBL1483294 | 0.82 | ESRRG (0.51) | ESRRGKMT2AMEN1MITFGAA | |
| SCHEMBL1483292 | 0.82 | ESRRG (0.51) | ESRRGKMT2AMEN1MITFGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636192-A1 | 3-ALKYLIDENEHYDRAZINO SUBSTITUTED HETEROARYL COMPOUNDS AS THROMBOPOIETIN RECEPTOR ACTIVATORS | Nissan Chemical Industries, Ltd. (JP) | 2006-03-22 | — | — | EP | disclosed |
| WO-2004108683-A1 | 3-ALKYLIDENEHYDRAZINO SUBSTITUTED HETEROARYL COMPOUNDS AS THROMBOPOIETIN RECEPTOR ACTIVATORS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2004-12-16 | — | — | WO | disclosed |