Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.69 |
| ▸ | EGFR | P00533 | 8/20 | 0.63 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.60 |
| ▸ | CNR2 | P34972 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | KDR | P35968 | 2/20 | 0.52 |
| ▸ | FLT1 | P17948 | 1/20 | 0.52 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.52 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5740105 | 0.89 | EGFR (0.69) | CNR1EGFRTRPV1MEN1KMT2A | |
| SCHEMBL11090480 | 0.87 | KDM4E (0.66) | CNR1EGFRKDM4EMEN1ALDH1A1 | |
| SCHEMBL5741563 | 0.86 | TRPV1 (0.56) | CNR1EGFRTRPV1KDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL11087390 | 0.86 | KDM4E (0.64) | CNR1EGFRKDM4EMEN1ALDH1A1 | |
| SCHEMBL5739486 | 0.84 | EGFR (0.63) | CNR1EGFRTRPV1KDM4EMEN1 | |
| SCHEMBL18292382 | 0.83 | MAP4K4 (0.62) | CNR1EGFRKDM4EMEN1ALDH1A1 | |
| SCHEMBL17557635 | 0.82 | CNR1 (1.00) | CNR1CNR2KDM4EMEN1ALDH1A1 | |
| SCHEMBL11091766 | 0.82 | MAPK1 (0.62) | EGFRKDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL29236930 | 0.82 | ABCG2 (0.64) | EGFRKDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL11084344 | 0.81 | EGFR (0.70) | EGFRKDM4EMEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1890223-A | Capsaicin receptor agonists | NEUROGEN CORP (US) | 2007-01-03 | — | — | CN | claimed |
| US-20060194805-A1 | Capsaicin receptor agonists | NEUROGEN CORPORATION (US) | 2006-08-31 | — | — | US | claimed |
| EP-1678149-A2 | 4-AMINO(AZA)QUINOLINE DERIVATIVES AS CAPSAICIN RECEPTOR AGONISTS | NEUROGEN CORPORATION (US) | 2006-07-12 | — | — | EP | claimed |
| WO-2005042498-A2 | 4-AMINO (AZA) QUINOLINE DERIVATIVES AS CAPSAICIN RECEPTOR AGONISTS | NEUROGEN CORPORATION (US) | 2005-05-12 | — | — | WO | claimed |
| US-20060194805-A1 | Capsaicin receptor agonists | NEUROGEN CORPORATION (US) | 2006-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060194805-A1 | Capsaicin receptor agonists | TRPV1, HCAR1, CNR1 | CNR1 3/4885EGFR 3398/4885TRPV1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.