Cyclohexane

Cyclohexane

SCHEMBL574083

C1CCCCC1.O=C(OCO)c1ccc(C(=O)OCO)cc1

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 4/20 0.49
KMT2A Q03164 4/20 0.47
MEN1 O00255 3/20 0.47
ESR1 P03372 2/20 0.47
CA12 O43570 1/20 0.47
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CA7 P43166 1/20 0.47
CA9 Q16790 1/20 0.47
ESR2 Q92731 1/20 0.47
CA14 Q9ULX7 1/20 0.47
LMNA P02545 2/20 0.45
CYP1A2 P05177 1/20 0.45
CYP3A4 P08684 1/20 0.45
MAOA P21397 1/20 0.45
CYP2D6 P10635 1/20 0.45
TDP1 Q9NUW8 4/20 0.44
ALDH1A1 P00352 3/20 0.44
SLC6A2 P23975 2/20 0.44
CHRM1 P11229 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6063284 0.93 ESR1 (0.52) RAB9AKMT2AMEN1ESR1CA12
Cyclohexane SCHEMBL6442295 0.92 MAPT (0.50) RAB9AKMT2AMEN1ESR1CA12
SCHEMBL14787328 0.86 ESR1 (0.47) RAB9AKMT2AMEN1ESR1CA12
SCHEMBL11188109 0.84 ESR1 (0.67) RAB9AKMT2AMEN1ESR1CA12
SCHEMBL27562916 0.84 TSHR (0.55) KMT2AMEN1ESR1CA12CA1
SCHEMBL6442300 0.84 SMN1; SMN2 (0.56) RAB9AKMT2AMEN1LMNAALDH1A1
SCHEMBL8680535 0.82 TDP1 (0.59) RAB9AKMT2AESR1CA12CA1
SCHEMBL8680210 0.82 GAA (0.54) RAB9AKMT2AMEN1ESR1CA1
SCHEMBL12446498 0.82 ESR1 (0.50) RAB9AKMT2AMEN1ESR1CA12
SCHEMBL12092863 0.82 CA1 (0.70) RAB9AKMT2AMEN1ESR1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240182683-A1 STABILIZER COMPOSITION, USE OF THE STABILIZER COMPOSITION, METHOD FOR STABILIZING CONDENSATION POLYMERS AGAINST HYDROLYTIC DEGRADATION, AND HYDROLYSIS-STABILIZED COMPOSITION AND MOLDING OR MOLDED PART CONSISTING THEREOF Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2024-06-06 US claimed
US-20240182674-A1 USE OF A STABILIZER COMPOSITION FOR STABILIZING HALOGEN-FREE RECYCLED THERMOPLASTICS, STABILIZER COMPOSITION, MASTER BATCH OR CONCENTRATE, STABILIZED PLASTIC COMPOSITION, PROCESS FOR STABILIZING HALOGEN-FREE RECYCLED THERMOPLASTICS, AND USE OF COMPOSITIONS Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2024-06-06 US claimed
EP-4308642-A1 STABILIZER COMPOSITION, USE OF THE STABILIZER COMPOSITION, METHOD FOR STABILIZING CONDENSATION POLYMERS AGAINST HYDROLYTIC DEGRADATION, AND HYDROLYSIS-STABILIZED COMPOSITION AND MOLDING OR MOLDED PART CONSISTING THEREOF Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2024-01-24 EP claimed
US-11781008-B2 Thermoplastic polyester elastomer resin composition for resin belt materials, and molded resin belt TORAY CELANESE CO., LTD. (JP) 2023-10-10 US claimed
US-20230263935-A1 NON-FIXED TYPE IMPLANT FOR CRANIOTOMY AND METHOD OF MANUFACTURING SAME T&R BIOFAB CO., LTD. (KR) 2023-08-24 US claimed
EP-4190281-A1 NON-FIXED TYPE IMPLANT FOR CRANIOTOMY AND METHOD OF MANUFACTURING SAME T&R Biofab Co., Ltd. (KR) 2023-06-07 EP claimed
US-11634560-B2 Efficient phosphorous stabilizers based on diphenylamine and heterocyclic diphenylamine derivatives Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2023-04-25 US claimed
WO-2022195041-A1 STABILIZER COMPOSITION, USE OF THE STABILIZER COMPOSITION, METHOD FOR STABILIZING CONDENSATION POLYMERS AGAINST HYDROLYTIC DEGRADATION, AND HYDROLYSIS-STABILIZED COMPOSITION AND MOLDING OR MOLDED PART CONSISTING THEREOF Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2022-09-22 WO claimed
US-20210130582-A1 EFFICIENT PHOSPHOROUS STABILISERS BASED ON DIPHENYLAMINE AND HETEROCYCLIC DIPHENYLAMINE DERIVATIVES Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2021-05-06 US claimed
EP-0593254-A2 Thermoplastic resin composition and process for producing the same Tonen Corporation (JP) 1994-04-20 EP claimed
US-3962368-A Linear polyester molding composition containing cross-linked linear polyester as a nucleating agent HOECHST AKTIENGESELLSCHAFT (DT) 1976-06-08 US claimed
US-20240182683-A1 STABILIZER COMPOSITION, USE OF THE STABILIZER COMPOSITION, METHOD FOR STABILIZING CONDENSATION POLYMERS AGAINST HYDROLYTIC DEGRADATION, AND HYDROLYSIS-STABILIZED COMPOSITION AND MOLDING OR MOLDED PART CONSISTING THEREOF Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2024-06-06 US disclosed
US-20240182674-A1 USE OF A STABILIZER COMPOSITION FOR STABILIZING HALOGEN-FREE RECYCLED THERMOPLASTICS, STABILIZER COMPOSITION, MASTER BATCH OR CONCENTRATE, STABILIZED PLASTIC COMPOSITION, PROCESS FOR STABILIZING HALOGEN-FREE RECYCLED THERMOPLASTICS, AND USE OF COMPOSITIONS Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2024-06-06 US disclosed
CN-116917410-A Antiviral resin composition containing hydrophilic polymer and molded body 东丽塞拉尼斯有限公司 2023-10-20 CN disclosed
US-11781008-B2 Thermoplastic polyester elastomer resin composition for resin belt materials, and molded resin belt TORAY CELANESE CO., LTD. (JP) 2023-10-10 US disclosed
US-4101601-A Epoxy-catalyst additive system to produce higher I.V. polybutylene terephthalate from low I.V. polymer CELANESE CORPORATION (US) 1978-07-18 US disclosed
US-4034013-A Impact and melt strength improvement of poly(alkylene terephthalate) ROHM AND HAAS COMPANY (US) 1977-07-05 US disclosed
US-3968307-A Mixed filaments KANEGAFUCHI BOSEKI KABUSHIKI KAISHA (JA) 1976-07-06 US disclosed
US-3962368-A Linear polyester molding composition containing cross-linked linear polyester as a nucleating agent HOECHST AKTIENGESELLSCHAFT (DT) 1976-06-08 US disclosed
US-3948831-A Dyeability of polyester textile fiber THE GOODYEAR TIRE & RUBBER COMPANY (US) 1976-04-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11634560-B2 Efficient phosphorous stabilizers based on diphenylamine and heterocyclic diphenylamine derivatives PNN, PNMT, PPA1 RAB9A 4295/4885KMT2A 1126/4885MEN1 3656/4885
US-20210130582-A1 EFFICIENT PHOSPHOROUS STABILISERS BASED ON DIPHENYLAMINE AND HETEROCYCLIC DIPHENYLAMINE DERIVATIVES PNMT, PNN, PPA1 RAB9A 4291/4885KMT2A 1021/4885MEN1 3573/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.