Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 1/20 | 0.69 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.66 |
| ▸ | PTPRC | P08575 | 1/20 | 0.63 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.63 |
| ▸ | PTPRB | P23467 | 1/20 | 0.63 |
| ▸ | PTPRE | P23469 | 1/20 | 0.63 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.63 |
| ▸ | CNR2 | P34972 | 2/20 | 0.62 |
| ▸ | CNR1 | P21554 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3914277 | 0.94 | FLT3 (0.77) | FLT3PTPN1KDM4EMAPTHSD17B10 | |
| SCHEMBL8290415 | 0.88 | FLT3 (0.90) | FLT3KDM4EMAPTHSD17B10CNR2 | |
| SCHEMBL3126680 | 0.88 | FLT3 (0.90) | FLT3KDM4EMAPTHSD17B10CNR2 | |
| SCHEMBL3128067 | 0.86 | FLT3 (0.92) | FLT3KDM4EMAPTHSD17B10CNR2 | |
| SCHEMBL3803667 | 0.85 | CNR2 (0.68) | FLT3KDM4EMAPTHSD17B10CNR2 | |
| SCHEMBL24426878 | 0.85 | KDM4E (0.64) | FLT3KDM4EMAPTHSD17B10CNR2 | |
| SCHEMBL8288684 | 0.85 | FLT3 (0.90) | FLT3KDM4EMAPTHSD17B10CNR2 | |
| SCHEMBL3760411 | 0.84 | PTPN1 (0.67) | FLT3PTPN1KDM4EMAPTHSD17B10 | |
| SCHEMBL29403396 | 0.84 | ALDH1A1 (0.76) | FLT3PTPN1MAPTPTPRCPTPN2 | |
| SCHEMBL5455726 | 0.83 | FLT3 (0.97) | FLT3KDM4EMAPTHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1670804-A2 | HETEROBICYCLIC COMPOUNDS AS PHARMACEUTICALLY ACTIVE AGENTS | GPC Biotech AG (DE) | 2006-06-21 | — | — | EP | disclosed |
| WO-2005023818-A2 | HETEROBICYCLIC COMPOUNDS AS PHARMACEUTICALLY ACTIVE AGENTS | GPC BIOTECH AG (DE) | 2005-03-17 | — | — | WO | disclosed |