Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 9/20 | 0.55 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.55 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | FNTA | P49354 | 1/20 | 0.45 |
| ▸ | FNTB | P49356 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | FABP3 | P05413 | 1/20 | 0.43 |
| ▸ | FABP4 | P15090 | 1/20 | 0.43 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.42 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5448641 | 0.91 | KMT2A (0.46) | DPP4DPP8DPP9ALDH1A1HPGD | |
| SCHEMBL5455705 | 0.91 | DPP4 (0.66) | DPP4DPP8DPP9ALDH1A1HPGD | |
| SCHEMBL5441585 | 0.88 | FABP3 (0.47) | DPP4DPP8DPP9ALDH1A1HPGD | |
| SCHEMBL5449433 | 0.88 | DPP4 (0.54) | DPP4DPP8DPP9ALDH1A1HPGD | |
| SCHEMBL5457960 | 0.86 | DPP4 (0.52) | DPP4DPP8DPP9ALDH1A1HPGD | |
| SCHEMBL5449831 | 0.85 | ALDH1A1 (0.42) | DPP4DPP8DPP9ALDH1A1HPGD | |
| SCHEMBL5457031 | 0.85 | DPP4 (0.51) | DPP4DPP8DPP9ALDH1A1HPGD | |
| SCHEMBL5454887 | 0.84 | DPP4 (0.54) | DPP4DPP8DPP9ALDH1A1HPGD | |
| SCHEMBL5454601 | 0.83 | DPP4 (0.56) | DPP4DPP8DPP9ALDH1A1HPGD | |
| SCHEMBL5444809 | 0.82 | DPP4 (0.57) | DPP4DPP8DPP9ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678138-A1 | PYRIDINE COMPOUNDS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE IV | Takeda Pharmaceutical Company Limited (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042488-A1 | PYRIDINE COMPOUNDS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE IV | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-05-12 | — | — | WO | disclosed |