Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 5/20 | 0.42 |
| ▸ | HTR3A | P46098 | 4/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.34 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.34 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3550610 | 0.90 | HTR1A (0.50) | HTR1AHTR3ASLC6A2SLC6A4SLC6A3 | |
| Trifluoroacetic Acid SCHEMBL3544105 | 0.89 | HTR1A (0.50) | HTR1AHTR3ASLC6A2SLC6A4SLC6A3 | |
| Trifluoroacetic Acid SCHEMBL5744789 | 0.85 | HTR1A (0.44) | HTR1AHTR3ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5742412 | 0.82 | HTR1A (0.38) | HTR1AHTR3AEPHX2SLC6A9LMNA | |
| Trifluoroacetic Acid SCHEMBL5743104 | 0.82 | SLC6A2 (0.39) | HTR1AHTR3ASLC6A2SLC6A4SLC6A3 | |
| Trifluoroacetic Acid SCHEMBL3544769 | 0.81 | HTR1A (0.47) | HTR1AHTR3ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3544502 | 0.80 | HTR1A (0.49) | HTR1AHTR3ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3542799 | 0.80 | HTR1A (0.51) | HTR1AHTR3ASLC6A2SLC6A4SLC6A3 | |
| Trifluoroacetic Acid SCHEMBL5742626 | 0.79 | SLC6A2 (0.42) | HTR1AHTR3ASLC6A2SLC6A4SLC6A3 | |
| Oxalic Acid SCHEMBL3539795 | 0.79 | HTR1A (0.53) | HTR1AHTR3ASLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1626720-A1 | 4-(2-PHENYLSULFANYL-PHENYL)-PIPERIDINE DERIVATIVES AS SEROTONIN REUPTAKE INHIBITORS | H. Lundbeck A/S (DK) | 2006-02-22 | — | — | EP | disclosed |
| WO-2004087156-A1 | 4-(2-PHENYLSULFANYL-PHENYL)-PIPERIDINE DERIVATIVES AS SEROTONIN REUPTAKE INHIBITORS | H. LUNDBECK A/S (DK) | 2004-10-14 | — | — | WO | disclosed |