SCHEMBL574246

SCHEMBL574246

CC(C)(c1cc(Br)c(OCC(Br)CBr)c(Br)c1)c1cc(Br)c(OCC(Br)CBr)c(Br)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 1.00
ALOX15 P16050 2/20 0.40
ALOX12 P18054 2/20 0.40
CYP3A4 P08684 1/20 0.40
HPGD P15428 1/20 0.40
TSHR P16473 1/20 0.40
CASP1 P29466 1/20 0.40
RECQL P46063 1/20 0.40
HIF1A Q16665 1/20 0.40
HSD17B10 Q99714 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
CHEK1 O14757 1/20 0.35
DAPK3 O43293 1/20 0.35
RET P07949 1/20 0.35
PDGFRB P09619 1/20 0.35
PIM1 P11309 1/20 0.35
PDGFRA P16234 1/20 0.35
KDR P35968 1/20 0.35
MAPK8 P45983 1/20 0.35
RPS6KA3 P51812 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28133374 0.88 ALDH1A1 (0.77) ALDH1A1ALOX15ALOX12CYP3A4HPGD
SCHEMBL5426562 0.85 ALDH1A1 (0.74) ALDH1A1TSHR
SCHEMBL11502472 0.84 ALDH1A1 (0.73) ALDH1A1ALOX15ALOX12CYP3A4HPGD
SCHEMBL6662636 0.81 ALDH1A1 (0.68) ALDH1A1TDP1THRATHRB
SCHEMBL5428071 0.80 ALDH1A1 (0.67) ALDH1A1TSHRTHRATHRB
SCHEMBL5440832 0.80 ALDH1A1 (0.67) ALDH1A1ALOX15ALOX12CYP3A4TSHR
SCHEMBL9807440 0.80 ALDH1A1 (0.66) ALDH1A1TSHR
SCHEMBL17076583 0.80 ALDH1A1 (0.66) ALDH1A1ALOX15ALOX12CYP3A4HPGD
SCHEMBL11192257 0.78 ALDH1A1 (0.64) ALDH1A1ALOX15ALOX12CYP3A4HPGD
SCHEMBL28421240 0.78 ALDH1A1 (0.64) ALDH1A1ALOX15TSHRHSD17B10THRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 821 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260078210-A1 PRECURSOR COMPOSITIONS COMPRISING A POLYMERIC MATERIAL, A BROMINE-CONTAINING FLAME RETARDANT, AND ANTIMONY TRIOXIDE NORTHROP GRUMMAN SYSTEMS CORP (US) 2026-03-19 US claimed
CN-120005142-A Polyurethane resin for compounding stone plastic plate and aluminum honeycomb, and preparation method and application thereof 佛山市桐立新材料科技有限公司 2025-05-16 CN claimed
CN-116622159-B Polypropylene composition and preparation method and application thereof 金发科技股份有限公司 2025-04-15 CN claimed
CN-119753870-A Preparation method of flame-retardant polyacrylonitrile fiber and flame-retardant polyacrylonitrile fiber 吉林富博纤维研究院有限公司 2025-04-04 CN claimed
CN-119708308-A High-melt-index high-Vicat polystyrene resin, and preparation method and application thereof 常州瑞华化工工程技术股份有限公司 2025-03-28 CN claimed
CN-116836505-B Modified polypropylene material and preparation method and application thereof 金发科技股份有限公司 2025-03-25 CN claimed
CN-118791367-B Directional high-value method for waste polyester product 浙江大学长三角智慧绿洲创新中心 2025-02-25 CN claimed
EP-4101881-B1 A METHOD AND INSTALLATION FOR RECYCLING A POLYSTYRENE BASED MATERIAL CONTAINING ORGANOHALOGEN FLAME RETARDANT AND/OR FREONEN Synthos Sa (PL) 2025-02-19 EP claimed
CN-119455319-A Water-based fire extinguishing agent composition and preparation method thereof 浙江永和制冷股份有限公司 2025-02-18 CN claimed
CN-119390924-A High heat-resistant flame-retardant polyurethane resin and preparation method thereof 万华化学集团股份有限公司 2025-02-07 CN claimed
EP-1449879-B1 FLAME−RETARDANT STYRENE RESIN COMPOSITION DAI ICHI KOGYO SEIYAKU CO LTD (JP) 2005-11-30 EP claimed
US-20040242736-A1 Flame-retardant sytrene resin composition ONISHI HIDEAKI (JP) 2004-12-02 US claimed
EP-1449880-A1 FLAME−RETARDANT STYRENE RESIN COMPOSITION Dai-Ichi Kogyo Seiyaku Co., Ltd. (JP) 2004-08-25 EP claimed
US-20040092642-A1 Flame-retardant styrene resin composition DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) 2004-05-13 US claimed
EP-0913381-A1 Method for purifying a bromine compound Teijin Chemicals, Ltd. (JP) 1999-05-06 EP claimed
US-4753970-A ORGANOHALOGENOUS COMPOUND AND CARBONIC ACID ESTER NIPPON KASEI CHEMICAL CO., LTD. (JP) 1988-06-28 US claimed
EP-0017711-B1 PROCESS FOR THE PREPARATION OF 2,2-BIS(4-(2,3-DIBROMOPROPOXY)-3,5-DIBROMOPHENYL) PROPANE RIEDEL-DE HAEN AKTIENGESELLSCHAFT (DE) 1982-04-07 EP claimed
US-4302614-A 2,2-Bis[4-(2,3-dibromopropoxy)-3,5-dibromophenyl]-propane process RIEDEL-DE HAEN AKTIENGESELLSCHAFT (DE) 1981-11-24 US claimed
WO-1980002844-A1 FIRE-PROOF ACRYLIC POLYMERS SANDOZ AG (CH) 1980-12-24 WO claimed
EP-0017711-A1 Process for the preparation of 2,2-bis(4-(2,3-dibromopropoxy)-3,5-dibromophenyl) propane RIEDEL-DE HAEN AKTIENGESELLSCHAFT (DE) 1980-10-29 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260078210-A1 PRECURSOR COMPOSITIONS COMPRISING A POLYMERIC MATERIAL, A BROMINE-CONTAINING FLAME RETARDANT, AND ANTIMONY TRIOXIDE AS3MT, RPL39, RPL24 ALDH1A1 1547/4885ALOX15 2877/4885ALOX12 2584/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.