Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 6/20 | 0.64 |
| ▸ | PTPRC | P08575 | 2/20 | 0.64 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.64 |
| ▸ | PTPRB | P23467 | 2/20 | 0.64 |
| ▸ | PTPRE | P23469 | 2/20 | 0.64 |
| ▸ | RAB7A | P51149 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.45 |
| ▸ | CFTR | P13569 | 1/20 | 0.43 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5446212 | 0.89 | CFTR (0.55) | PTPN1PTPRCPTPN2PTPRBPTPRE | |
| SCHEMBL5458466 | 0.88 | ALDH1A1 (0.55) | PTPN1PTPRCPTPN2PTPRBPTPRE | |
| SCHEMBL3760411 | 0.83 | PTPN1 (0.67) | PTPN1PTPRCPTPN2PTPRBPTPRE | |
| SCHEMBL5453432 | 0.81 | PTPN1 (0.71) | PTPN1PTPRCPTPN2PTPRBPTPRE | |
| SCHEMBL5460559 | 0.80 | CFTR (0.55) | PTPN1PTPRCPTPN2PTPRBPTPRE | |
| SCHEMBL4312414 | 0.78 | PTPN1 (1.00) | PTPN1PTPRCPTPN2PTPRBPTPRE | |
| SCHEMBL5741314 | 0.78 | PTPN1 (0.75) | PTPN1PTPRCPTPN2PTPRBPTPRE | |
| SCHEMBL5451081 | 0.77 | ALDH1A1 (0.54) | PTPN1PTPRCPTPN2PTPRBPTPRE | |
| SCHEMBL7854135 | 0.77 | PTPN1 (0.58) | PTPN1PTPRCPTPN2PTPRBPTPRE | |
| SCHEMBL4090461 | 0.77 | CNR2 (0.70) | PTPN1PTPRCPTPN2PTPRBPTPRE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1670804-A2 | HETEROBICYCLIC COMPOUNDS AS PHARMACEUTICALLY ACTIVE AGENTS | GPC Biotech AG (DE) | 2006-06-21 | — | — | EP | disclosed |
| WO-2005023818-A2 | HETEROBICYCLIC COMPOUNDS AS PHARMACEUTICALLY ACTIVE AGENTS | GPC BIOTECH AG (DE) | 2005-03-17 | — | — | WO | disclosed |