Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.37 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5475204 | 0.87 | KMT2A (0.83) | KMT2AOPRM1 | |
| SCHEMBL4878379 | 0.86 | KMT2A (0.68) | KMT2AADRB1OPRM1OPRD1OPRK1 | |
| Hydrochloric Acid SCHEMBL3249332 | 0.85 | KMT2A (0.67) | KMT2AADRB1OPRM1OPRD1OPRK1 | |
| SCHEMBL5473344 | 0.82 | KMT2A (0.61) | KMT2AOPRM1ALDH1A1 | |
| SCHEMBL5475970 | 0.82 | KMT2A (0.61) | KMT2AALDH1A1 | |
| SCHEMBL5480849 | 0.81 | OPRM1 (0.60) | KMT2AOPRM1OPRL1ALDH1A1 | |
| SCHEMBL5742585 | 0.81 | KMT2A (0.65) | KMT2AADRB1OPRM1ALDH1A1HTR2C | |
| SCHEMBL11814914 | 0.80 | KMT2A (1.00) | KMT2AOPRM1 | |
| Hydrochloric Acid SCHEMBL4880648 | 0.80 | KMT2A (0.63) | KMT2AADRB1OPRM1ALDH1A1HTR2C | |
| SCHEMBL1007128 | 0.79 | KMT2A (0.78) | KMT2AOPRM1OPRD1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1736467-A1 | NOVEL SULFONAMIDE DERIVATIVE | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2006-12-27 | — | — | EP | disclosed |
| EP-1679069-A1 | NOVEL PIPERIDINE DERIVATIVE | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2006-07-12 | — | — | EP | disclosed |