Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 7/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | AQP1 | P29972 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 10/20 | 0.46 |
| ▸ | CA12 | O43570 | 6/20 | 0.40 |
| ▸ | CA1 | P00915 | 6/20 | 0.40 |
| ▸ | CA3 | P07451 | 6/20 | 0.40 |
| ▸ | CA6 | P23280 | 6/20 | 0.40 |
| ▸ | CA7 | P43166 | 6/20 | 0.40 |
| ▸ | CA13 | Q8N1Q1 | 6/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2741903 | 0.94 | CA2 (0.56) | CA2KDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL2741900 | 0.94 | CA2 (0.58) | CA2KDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL2741897 | 0.94 | CA2 (0.55) | CA2KDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL230463 | 0.93 | CA2 (0.52) | CA2KDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL2741899 | 0.93 | CA2 (0.54) | CA2KDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL2741911 | 0.92 | CA2 (0.53) | CA2KDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL2741901 | 0.92 | CA2 (0.54) | CA2KDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL2741904 | 0.89 | CA2 (0.52) | CA2KDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL2741896 | 0.89 | KDM4E (0.57) | CA2KDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL18993673 | 0.87 | CA2 (0.49) | CA2KDM4EUSP2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2598478-A2 | ARYLSULFONAMIDE DERIVATIVES, COMPOSITIONS, AND METHODS OF USE | Neurotherapeutics Pharma, Inc. (US) | 2013-06-05 | — | — | EP | disclosed |
| WO-2012018635-A2 | ARYLSULFONAMIDE DERIVATIVES, COMPOSITIONS, AND METHODS OF USE | NEUROTHERAPEUTICS PHARMA, INC. (US) | 2012-02-09 | — | — | WO | disclosed |