⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL3720314 | 0.97 | — | — | |
| Sulfuric Acid SCHEMBL6192522 | 0.85 | — | — | |
| Methane SCHEMBL11357049 | 0.62 | — | — | |
| Hydrochloric Acid SCHEMBL6656237 | 0.62 | — | — | |
| SCHEMBL2097733 | 0.62 | — | — | |
| Hydrochloric Acid SCHEMBL6922206 | 0.62 | — | — | |
| Iodide SCHEMBL22322572 | 0.61 | — | — | |
| Ethane SCHEMBL11360563 | 0.61 | — | — | |
| SCHEMBL8673272 | 0.61 | — | — | |
| Pyridazine SCHEMBL22282647 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242424-B1 | PROCESS FOR THE PREPARATION OF PYRAZOLO[1,5-B]PYRIDAZINE DERIVATIVES | GLAXO GROUP LTD (GB) | 2005-07-13 | — | — | EP | claimed |
| US-6803463-B2 | Process for the preparation of pyrazolopyridine derivatives | SMITHKLINE BEECHAM CORPORATION | 2004-10-12 | — | — | US | claimed |
| US-20030078267-A1 | Process for the preparation of pyrazolopyridine derivatives | SMITHKLINE BEECHAM CORPORATION | 2003-04-24 | — | — | US | claimed |
| EP-1242424-A2 | PROCESS FOR THE PREPARATION OF PYRAZOLO[1,5-B]PYRIDAZINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2002-09-25 | — | — | EP | claimed |
| WO-2001046194-A2 | PROCESS FOR THE PREPARATION OF PYRAZOLO[1,5-B]PYRIDAZINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2001-06-28 | — | — | WO | claimed |
| JP-58134094-A | — | — | None | — | — | JP | disclosed |
| US-12577243-B2 | Monoacylglycerol lipase modulators | JANSSEN PHARMACEUTICA NV (BE) | 2026-03-17 | — | — | US | disclosed |
| EP-3856178-B1 | MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2026-03-11 | — | — | EP | disclosed |
| CN-113164459-B | Monoacylglycerol lipase modulators | 詹森药业有限公司 | 2024-09-03 | — | — | CN | disclosed |
| US-11820766-B2 | Monoacylglycerol lipase modulators | JANSSEN PHARMACEUTICA NV (BE) | 2023-11-21 | — | — | US | disclosed |
| US-11820766-B2 | Monoacylglycerol lipase modulators | JANSSEN PHARMACEUTICA NV (BE) | 2023-11-21 | — | — | US | disclosed |
| EP-3684776-B1 | HETEROCYCLYL SUBSTITUTED PYRROLOPYRIDINES THAT ARE INHIBITORS OF THE CDK12 KINASE | UNIV NOTTINGHAM (GB) | 2023-11-01 | — | — | EP | disclosed |
| US-20030040517-A1 | 2,3-Diaryl-pyrazolo[1,5-b]pyridazines derivatives, their preparation and their use as cyclooxygenase 2 (COX-2) inhibirors | SMITHKLINE BEECHAM CORPORATION | 2003-02-27 | — | — | US | disclosed |
| US-20030008872-A1 | 2,3-Diaryl-pyrazolo[1,5-B]pyridazines derivatives, their preparation and their use as cyclooxygenase 2 (COX-2) inhibitors | BESWICK PAUL JOHN (GB) | 2003-01-09 | — | — | US | disclosed |
| EP-1242424-A2 | PROCESS FOR THE PREPARATION OF PYRAZOLO[1,5-B]PYRIDAZINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2002-09-25 | — | — | EP | disclosed |
| US-6451794-B1 | 2,3-Diaryl-pyrazolo[1,5-b]pyridazines derivatives, their preparation and their use as cyclooxygenase 2(COX-2) inhibitors | SMITHKLINE BEECHAM CORPORATION | 2002-09-17 | — | — | US | disclosed |
| WO-2001046194-A2 | PROCESS FOR THE PREPARATION OF PYRAZOLO[1,5-B]PYRIDAZINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2001-06-28 | — | — | WO | disclosed |
| EP-1032575-A1 | 2,3-DIARYL-PYRAZOLO(1,5-B)PYRIDAZINES DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYCLOOXYGENASE 2 (COX-2) INHIBITORS | GLAXO GROUP LIMITED (GB) | 2000-09-06 | — | — | EP | disclosed |
| WO-1999012930-A1 | 2,3-DIARYL-PYRAZOLO[1,5-B]PYRIDAZINES DERIVATIVES, THEIR PREPA RATION AND THEIR USE AS CYCLOOXYGENASE 2 (COX-2) INHIBITORS | GLAXO GROUP LIMITED (GB) | 1999-03-18 | — | — | WO | disclosed |
| JP-S58134094-A | 3-FORMYL-PYRAZOLO(1,5-B)PYRIDAZINE DERIVATIVE AND PREPARATION THEREOF | MITSUBISHI PAPER MILLS LTD | 1983-08-10 | — | — | JP | disclosed |