⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8632065 | 0.67 | — | — | |
| SCHEMBL8653798 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL8636532 | 0.65 | — | — | |
| Hydrochloric Acid SCHEMBL4436015 | 0.63 | — | — | |
| Pyridine SCHEMBL28350541 | 0.61 | TSHR (0.47) | — | |
| Hydrochloric Acid SCHEMBL6656237 | 0.61 | — | — | |
| SCHEMBL2097733 | 0.61 | — | — | |
| SCHEMBL5742967 | 0.61 | — | — | |
| Methane SCHEMBL11357049 | 0.61 | — | — | |
| Hydrochloric Acid SCHEMBL6922206 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112543764-B | Amide compound with BET proteolytic induction effect and medical application thereof | 田边三菱制药株式会社 | 2024-05-10 | — | — | CN | disclosed |
| CN-112543764-A | Amide compound with BET proteolysis induction effect and medical application thereof | 田边三菱制药株式会社 | 2021-03-23 | — | — | CN | disclosed |
| EP-3535253-A1 | 1,3-DIHYDRO-1,4-BENZODIAZEPINE-2-THIONES FOR THE TREATMENT OF CNS RELATED DISEASES | H. Hoffnabb-La Roche Ag (CH) | 2019-09-11 | — | — | EP | disclosed |
| US-5760032-A | GASTROINTESTINAL DISORDERS AND NERVOUS SYSTEM DISORDERS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-06-02 | — | — | US | disclosed |
| US-5753649-A | Therapeutic agent for osteoporosis and diazepine compound | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-05-19 | — | — | US | disclosed |
| US-5532233-A | PLATELET ACTIVATING FACTOR ANTAGONIST | BOEHRINGER INGELHEIM KG (DE) | 1996-07-02 | — | — | US | disclosed |
| US-4914096-A | INHIBITORS OF PLATELET ACTIVATING FACTOR | SANDOZ PHARMACEUTICALS CORP. (US) | 1990-04-03 | — | — | US | disclosed |
| EP-0338993-A1 | 6-Aryl-substituted-4h-thieno[2,3-e][1,2,4]triazolo [3,4-c][1,4]diazepines | SANDOZ AG (CH) | 1989-10-25 | — | — | EP | disclosed |
| EP-0338993-A1 | 6-Aryl-substituted-4h-thieno[2,3-e][1,2,4]triazolo [3,4-c][1,4]diazepines | SANDOZ AG (CH) | 1989-10-25 | — | — | EP | disclosed |