Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.78 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.58 |
| ▸ | MTOR | P42345 | 3/20 | 0.57 |
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | KIF11 | P52732 | 1/20 | 0.56 |
| ▸ | TGM2 | P21980 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RORC | P51449 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | NAMPT | P43490 | 1/20 | 0.54 |
| ▸ | CNR1 | P21554 | 1/20 | 0.54 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11003408 | 0.88 | EPHX2 (1.00) | EPHX2MEN1KMT2AMAPTCA12 | |
| SCHEMBL28729179 | 0.88 | EPHX2 (1.00) | EPHX2MEN1KMT2AMAPTCA12 | |
| SCHEMBL4922162 | 0.83 | EPHX2 (0.81) | EPHX2MEN1KMT2AMAPTCA12 | |
| SCHEMBL12491371 | 0.82 | EPHX2 (0.81) | EPHX2MEN1KMT2AMAPTCA12 | |
| SCHEMBL12413880 | 0.81 | EPHX2 (0.78) | EPHX2MEN1KMT2AMAPTCA12 | |
| SCHEMBL5809373 | 0.81 | EPHX2 (0.85) | EPHX2MEN1KMT2AMAPTCA12 | |
| SCHEMBL7524681 | 0.81 | EPHX2 (0.78) | EPHX2MEN1KMT2AMAPTCA12 | |
| SCHEMBL18031166 | 0.81 | EPHX2 (0.85) | EPHX2MEN1KMT2AMAPTCA12 | |
| SCHEMBL4548071 | 0.81 | EPHX2 (0.85) | EPHX2MEN1KMT2AMAPTCA12 | |
| SCHEMBL9835395 | 0.80 | EPHX2 (0.70) | EPHX2MEN1KMT2AMAPTCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103570723-A | Pyrazolopyrimidine derivative, its preparation method, and its use in preparation of medicines | UNIV SICHUAN | 2014-02-12 | — | — | CN | disclosed |
| EP-1727541-A1 | IMIDAZOLE-BASED HMG-COA REDUCTASE INHIBITORS | Warner-Lambert Company LLC (US) | 2006-12-06 | — | — | EP | disclosed |
| WO-2006059210-A2 | FUSED BICYCLIC PYRROLS AS HMG-COA REDUCTASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2006-06-08 | — | — | WO | disclosed |
| WO-2005079790-A1 | IMIDAZOLE-BASED HMG-COA REDUCTASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2005-09-01 | — | — | WO | disclosed |