Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 20/20 | 0.65 |
| ▸ | NR3C1 | P04150 | 19/20 | 0.65 |
| ▸ | NR3C2 | P08235 | 9/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL291446 | 0.88 | PGR (0.75) | PGRNR3C1NR3C2 | |
| SCHEMBL291078 | 0.79 | PGR (1.00) | PGRNR3C1NR3C2 | |
| SCHEMBL6583575 | 0.78 | PGR (0.78) | PGRNR3C1NR3C2 | |
| SCHEMBL6583606 | 0.75 | PGR (0.82) | PGRNR3C1NR3C2 | |
| SCHEMBL1932108 | 0.75 | PGR (0.68) | PGRNR3C1NR3C2 | |
| SCHEMBL293245 | 0.74 | PGR (0.86) | PGRNR3C1NR3C2 | |
| SCHEMBL6584862 | 0.74 | PGR (0.82) | PGRNR3C1NR3C2 | |
| SCHEMBL27498148 | 0.74 | PGR (0.72) | PGRNR3C1NR3C2 | |
| SCHEMBL6554312 | 0.74 | PGR (1.00) | PGRNR3C1NR3C2 | |
| SCHEMBL27482405 | 0.74 | PGR (0.87) | PGRNR3C1NR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1467982-B1 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL FORMULATIONS CONTAINING THEM, AND USES THEREOF | BOEHRINGER INGELHEIM PHARMA (US) | 2006-11-22 | — | — | EP | claimed |