Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.34 |
| ▸ | KDM4A | O75164 | 1/20 | 0.34 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.34 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5743375 | 0.98 | LCK (0.38) | LCKLMNAPLA2G1BPLA2G2ACHRM2 | |
| Hydrochloric Acid SCHEMBL6239248 | 0.98 | LCK (0.38) | LCKLMNAPLA2G1BPLA2G2ACHRM2 | |
| SCHEMBL6549705 | 0.91 | CHRM2 (0.41) | LMNAPLA2G1BPLA2G2ACHRM2TRPV1 | |
| SCHEMBL5859495 | 0.91 | CHRM2 (0.41) | LMNAPLA2G1BPLA2G2ACHRM2TRPV1 | |
| SCHEMBL5860606 | 0.91 | CHRM2 (0.41) | LMNAPLA2G1BPLA2G2ACHRM2TRPV1 | |
| SCHEMBL13738322 | 0.91 | CHRM2 (0.41) | LMNAPLA2G1BPLA2G2ACHRM2TRPV1 | |
| SCHEMBL5859378 | 0.91 | CHRM2 (0.41) | LMNAPLA2G1BPLA2G2ACHRM2TRPV1 | |
| SCHEMBL29055677 | 0.91 | LCK (0.41) | LCKLMNAPLA2G1BPLA2G2A | |
| SCHEMBL5860262 | 0.88 | LMNA (0.40) | LCKLMNAPLA2G1BPLA2G2ACHRM2 | |
| SCHEMBL139908 | 0.88 | LMNA (0.48) | LMNAPLA2G1BPLA2G2ATRPV1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1463707-A4 | A GROUP OF NOVEL ANTI-CANCER COMPOUNDS WITH SPECIFIC STRUCTURE | YANG ZHENHUA (US) | 2006-02-01 | — | — | EP | disclosed |
| EP-1463707-A2 | A GROUP OF NOVEL ANTI-CANCER COMPOUNDS WITH SPECIFIC STRUCTURE | Yang, Zhenhua (US) | 2004-10-06 | — | — | EP | disclosed |
| WO-2003014296-A2 | A GROUP OF NOVEL ANTI-CANCER COMPOUNDS WITH SPECIFIC STRUCTURE | YANG ZHENHUA (US) | 2003-02-20 | — | — | WO | disclosed |