SCHEMBL5743744

SCHEMBL5743744

CCOC(=O)NC1(CN2CCN(S(=O)(=O)C3=Cc4ccc(Br)cc4OC3)CC2=O)CCN(c2ccncc2)CC1

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
F10 P00742 2/20 0.32
ITGB3 P05106 1/20 0.30
ITGA2B P08514 1/20 0.30
LMNA P02545 1/20 0.30
LSS P48449 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5743335 0.99 F10 (0.32) F10ITGB3ITGA2B
SCHEMBL5743460 0.93 F10 (0.31) F10
Hydrochloric Acid SCHEMBL5743496 0.92 F10 (0.32) F10
SCHEMBL5740694 0.92 F10 (0.36) F10
SCHEMBL5757205 0.87 F10 (0.35) F10ITGB3ITGA2B
SCHEMBL5741415 0.86 F10 (0.37) F10ITGB3ITGA2B
Hydrochloric Acid SCHEMBL6894610 0.84 F10 (0.33) F10ITGB3ITGA2BLSS
SCHEMBL5742755 0.84 LSS (0.44) F10ITGB3ITGA2BLMNALSS
SCHEMBL5744431 0.83 F10 (0.43) F10LSS
Hydrochloric Acid SCHEMBL5743226 0.83 F10 (0.34) F10LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7109200-B2 Carbamate derivatives, process for producing the same and use thereof TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2006-09-19 US disclosed
EP-1340753-B1 CARBAMATE DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND USE THEREOF TAKEDA PHARMACEUTICAL (JP) 2006-01-11 EP disclosed
US-20040038986-A1 Carbamate derivatives, process for producing the same and use thereof TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2004-02-26 US disclosed
EP-1340753-A1 CARBAMATE DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND USE THEREOF Takeda Chemical Industries, Ltd. (JP) 2003-09-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040038986-A1 Carbamate derivatives, process for producing the same and use thereof CFH, F11, F2 F10 4/4885ITGB3 1001/4885ITGA2B 882/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.