Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 5/20 | 0.84 |
| ▸ | AVPR1A | P37288 | 5/20 | 0.84 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP7 | P09237 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 5/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.34 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.33 |
| ▸ | SCD | O00767 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5743869 | 1.00 | OXTR (0.84) | OXTRAVPR1AMMP1MMP3MMP7 | |
| SCHEMBL7088497 | 1.00 | OXTR (0.84) | OXTRAVPR1AMMP1MMP3MMP7 | |
| SCHEMBL7162141 | 0.93 | OXTR (0.73) | OXTRAVPR1AMMP1MMP3MMP7 | |
| SCHEMBL4943198 | 0.91 | OXTR (1.00) | OXTRAVPR1AMMP1MMP3MMP7 | |
| SCHEMBL4936354 | 0.91 | OXTR (1.00) | OXTRAVPR1AMMP1MMP3MMP7 | |
| SCHEMBL4942975 | 0.91 | OXTR (1.00) | OXTRAVPR1AMMP1MMP3MMP7 | |
| SCHEMBL4936174 | 0.91 | OXTR (1.00) | OXTRAVPR1AMMP1MMP3MMP7 | |
| SCHEMBL5743785 | 0.91 | OXTR (1.00) | OXTRAVPR1AMMP1MMP3MMP7 | |
| SCHEMBL5743780 | 0.91 | OXTR (1.00) | OXTRAVPR1AMMP1MMP3MMP7 | |
| SCHEMBL4940385 | 0.91 | OXTR (1.00) | OXTRAVPR1AMMP1MMP3MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1268419-B1 | PYRROLIDINE DERIVATIVES USEFUL AS BAX INHIBITORS | APPLIED RESEARCH SYSTEMS (AN) | 2006-06-21 | — | — | EP | claimed |