Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 5/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
| ▸ | PRKCG | P05129 | 1/20 | 0.38 |
| ▸ | PRKCB | P05771 | 1/20 | 0.38 |
| ▸ | IL1R1 | P14778 | 1/20 | 0.38 |
| ▸ | PRKCA | P17252 | 1/20 | 0.38 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.38 |
| ▸ | PRKCH | P24723 | 1/20 | 0.38 |
| ▸ | PRKCI | P41743 | 1/20 | 0.38 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.38 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.38 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.38 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.38 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5628931 | 0.92 | MRGPRX4 (0.41) | CNR1MRGPRX4KDM4EMAPTPRKD3 | |
| SCHEMBL5628938 | 0.92 | MRGPRX4 (0.41) | CNR1MRGPRX4KDM4EMAPTPRKD3 | |
| SCHEMBL5745896 | 0.79 | HRH3 (0.46) | MAPTHIF1A | |
| SCHEMBL20822846 | 0.74 | MAPK8 (0.47) | KDM4EMAPTGAA | |
| SCHEMBL26935197 | 0.74 | HIF1A (0.40) | HIF1A | |
| SCHEMBL7172796 | 0.73 | HIF1A (0.53) | HIF1A | |
| SCHEMBL7172790 | 0.73 | HIF1A (0.53) | HIF1A | |
| SCHEMBL5741743 | 0.72 | MEN1 (0.47) | KDM4EMAPT | |
| SCHEMBL5742294 | 0.72 | KMT2A (0.48) | KDM4EMAPTGAA | |
| SCHEMBL19473604 | 0.72 | LMNA (0.40) | MRGPRX4HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1453817-B1 | THIAZOLE DERIVATIVES WITH FUNGICIDAL ACTIVITY | ISAGRO RICERCA SRL (IT) | 2006-04-26 | — | — | EP | claimed |