Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 5/20 | 0.60 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MARS2 | Q96GW9 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RPLP1 | P05386 | 1/20 | 0.40 |
| ▸ | RPLP0 | P05388 | 1/20 | 0.40 |
| ▸ | RPS17 | P08708 | 1/20 | 0.40 |
| ▸ | RPSA | P08865 | 1/20 | 0.40 |
| ▸ | RPS2 | P15880 | 1/20 | 0.40 |
| ▸ | RPL35A | P18077 | 1/20 | 0.40 |
| ▸ | RPL7 | P18124 | 1/20 | 0.40 |
| ▸ | RPL17 | P18621 | 1/20 | 0.40 |
| ▸ | RPS4Y1 | P22090 | 1/20 | 0.40 |
| ▸ | RPS3 | P23396 | 1/20 | 0.40 |
| ▸ | RPS12 | P25398 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4939070 | 1.00 | OXTR (0.60) | OXTRAVPR1ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL5744303 | 1.00 | OXTR (0.60) | OXTRAVPR1ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL4938413 | 0.93 | OXTR (0.53) | OXTRAVPR1ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL4936808 | 0.93 | OXTR (0.62) | OXTRAVPR1ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL4944113 | 0.91 | OXTR (0.71) | OXTRAVPR1ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL4944077 | 0.86 | OXTR (0.63) | OXTRAVPR1AMAPK1 | |
| SCHEMBL7090233 | 0.86 | OXTR (0.63) | OXTRAVPR1AMAPK1 | |
| SCHEMBL4944075 | 0.86 | OXTR (0.63) | OXTRAVPR1AMAPK1 | |
| SCHEMBL4944290 | 0.85 | OXTR (0.62) | OXTRAVPR1ACYP3A4TSHR | |
| SCHEMBL4944293 | 0.85 | OXTR (0.62) | OXTRAVPR1ACYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1268419-B1 | PYRROLIDINE DERIVATIVES USEFUL AS BAX INHIBITORS | APPLIED RESEARCH SYSTEMS (AN) | 2006-06-21 | — | — | EP | claimed |