Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TSPO | P30536 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5746219 | 0.91 | PPARG (0.40) | PPARGMCL1LMNAMAPTGAA | |
| SCHEMBL5745145 | 0.85 | PPARG (0.55) | PPARGMCL1LMNAMAPTGAA | |
| SCHEMBL6847052 | 0.85 | PPARG (0.54) | PPARGMCL1LMNAGAASMN1; SMN2 | |
| SCHEMBL5746078 | 0.84 | PPARG (0.53) | PPARGMCL1LMNAMAPTGAA | |
| SCHEMBL5747345 | 0.79 | PPARG (0.54) | PPARGMCL1LMNAGAASMN1; SMN2 | |
| SCHEMBL5747320 | 0.79 | PPARG (0.50) | PPARGMCL1LMNAGAASMN1; SMN2 | |
| SCHEMBL5798279 | 0.78 | PPARG (0.46) | PPARGMCL1LMNAMAPTGAA | |
| SCHEMBL5746660 | 0.78 | PPARG (0.48) | PPARGMCL1LMNAGAAMAPK1 | |
| SCHEMBL6847175 | 0.77 | PPARG (0.54) | PPARGMCL1LMNAMAPTGAA | |
| SCHEMBL6847051 | 0.76 | PPARG (0.43) | PPARGMCL1LMNAGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1173427-B1 | HYDROXAMIC ACID DERIVATIVE | DAINIPPON SUMITOMO PHARMA CO (JP) | 2006-04-05 | — | — | EP | disclosed |
| US-6713477-B1 | 1,4-BENZTHIAZINES OR BENZOXAZINES; MATRIX METALLOPROTEINASE INHIBITORS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2004-03-30 | — | — | US | disclosed |