Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5798279 | 0.92 | PPARG (0.46) | PPARGMCL1GAAHSD17B3SMN1; SMN2 | |
| SCHEMBL6847175 | 0.91 | PPARG (0.54) | PPARGMCL1GAAHSD17B3SMN1; SMN2 | |
| SCHEMBL6847051 | 0.90 | PPARG (0.43) | PPARGMCL1GAAHSD17B3SMN1; SMN2 | |
| SCHEMBL6847052 | 0.89 | PPARG (0.54) | PPARGMCL1GAAHSD17B3SMN1; SMN2 | |
| SCHEMBL5746078 | 0.88 | PPARG (0.53) | PPARGMCL1GAAHSD17B3SMN1; SMN2 | |
| SCHEMBL5744982 | 0.85 | PPARG (0.51) | PPARGMCL1GAASMN1; SMN2LMNA | |
| SCHEMBL5747320 | 0.84 | PPARG (0.50) | PPARGMCL1GAAHSD17B3SMN1; SMN2 | |
| SCHEMBL5747345 | 0.83 | PPARG (0.54) | PPARGMCL1GAAHSD17B3SMN1; SMN2 | |
| SCHEMBL5744163 | 0.82 | MCL1 (0.52) | PPARGMCL1GAAHSD17B3SMN1; SMN2 | |
| SCHEMBL5747025 | 0.81 | PPARG (0.45) | PPARGMCL1GAAHSD17B3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1173427-B1 | HYDROXAMIC ACID DERIVATIVE | DAINIPPON SUMITOMO PHARMA CO (JP) | 2006-04-05 | — | — | EP | disclosed |
| US-6713477-B1 | 1,4-BENZTHIAZINES OR BENZOXAZINES; MATRIX METALLOPROTEINASE INHIBITORS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2004-03-30 | — | — | US | disclosed |