Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.46 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
| ▸ | NQO1 | P15559 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1150948 | 0.82 | PTPN22 (0.52) | PTPN22LDHANQO1TDP1MEN1 | |
| SCHEMBL18263183 | 0.78 | POLB (0.59) | POLBPTPN22LDHATDP1HSD17B10 | |
| SCHEMBL1776619 | 0.77 | POLB (0.36) | POLBPTPN22LDHAMEN1MAPT | |
| SCHEMBL374807 | 0.77 | PTPN22 (0.65) | POLBPTPN22LDHATDP1HSD17B10 | |
| SCHEMBL29401627 | 0.77 | PTPN22 (0.65) | POLBPTPN22LDHATDP1HSD17B10 | |
| SCHEMBL18263218 | 0.75 | PTPN22 (0.48) | POLBPTPN22LDHAMAPK1ALDH1A1 | |
| SCHEMBL1840828 | 0.75 | PTPN22 (0.62) | POLBPTPN22LDHATDP1HSD17B10 | |
| SCHEMBL9060860 | 0.75 | PTPN22 (0.62) | POLBPTPN22LDHATDP1HSD17B10 | |
| SCHEMBL5155985 | 0.75 | PTPN22 (0.62) | POLBPTPN22LDHATDP1HSD17B10 | |
| SCHEMBL22534465 | 0.74 | PTPN22 (0.57) | POLBPTPN22LDHATDP1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2004622-B1 | CHIRAL BINAPHTHYL SULFATES FOR USE AS LIQUID CRYSTAL MATERIALS | MERCK PATENT GMBH (DE) | 2011-12-14 | — | — | EP | claimed |
| CN-113474321-B | Compound having binaphthyl skeleton and method for producing compound having binaphthyl skeleton | 帝人株式会社 | 2023-12-15 | — | — | CN | disclosed |
| CN-110770226-B | Sulfoximine glycosidase inhibitors | 阿森纽荣股份公司 | 2023-11-10 | — | — | CN | disclosed |
| CN-113474321-A | Compound having binaphthyl skeleton and method for producing compound having binaphthyl skeleton | 帝人株式会社 | 2021-10-01 | — | — | CN | disclosed |
| CN-113166083-A | Succinate and fumarate acid addition salts of piperazine derivatives as glycosidase inhibitors | 阿森纽荣股份公司 | 2021-07-23 | — | — | CN | disclosed |
| CN-110770226-A | Sulfoximine glycosidase inhibitors | 阿森纽荣股份公司 | 2020-02-07 | — | — | CN | disclosed |
| EP-1151987-B1 | OPTICALLY ACTIVE FLUORINATED BINAPHTHOL DERIVATIVE | JAPAN SCIENCE & TECH AGENCY (JP) | 2006-10-25 | — | — | EP | disclosed |
| US-6476250-B1 | Optically active fluorinated binaphthol derivative | JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) | 2002-11-05 | — | — | US | disclosed |
| EP-1151987-A1 | OPTICALLY ACTIVE FLUORINATED BINAPHTHOL DERIVATIVE | Japan Science and Technology Corporation (JP) | 2001-11-07 | — | — | EP | disclosed |