Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.35 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.35 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.34 |
| ▸ | LDHA | P00338 | 1/20 | 0.34 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | MPL | P40238 | 1/20 | 0.32 |
| ▸ | CTRC | Q99895 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | CDK8 | P49336 | 1/20 | 0.32 |
| ▸ | NEK2 | P51955 | 1/20 | 0.32 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.32 |
| ▸ | STAT3 | P40763 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5745253 | 0.77 | POLB (0.47) | POLBPTPN22LDHADHFRMEN1 | |
| SCHEMBL8770818 | 0.70 | ERN1 (0.49) | POLBPTPN22MPLCTRCMEN1 | |
| SCHEMBL8770826 | 0.70 | SLC22A6 (0.47) | CTRB1PTPN22LDHAMPLCTRC | |
| SCHEMBL18263183 | 0.67 | POLB (0.59) | POLBPTPN22LDHAALDH1A1 | |
| SCHEMBL11765036 | 0.67 | SLC22A6 (0.47) | ALDH1A1MAPTKDM4EGAANCEH1 | |
| SCHEMBL28781899 | 0.66 | CA12 (0.46) | POLBCTRB1PTPN22DNMT1LDHA | |
| SCHEMBL374807 | 0.66 | PTPN22 (0.65) | POLBPTPN22LDHAALDH1A1 | |
| SCHEMBL29401627 | 0.66 | PTPN22 (0.65) | POLBPTPN22LDHAALDH1A1 | |
| SCHEMBL22207936 | 0.65 | TSHR (0.46) | ALDH1A1NCEH1 | |
| SCHEMBL8017323 | 0.65 | SLC22A6 (0.42) | POLBMEN1ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2004622-B1 | CHIRAL BINAPHTHYL SULFATES FOR USE AS LIQUID CRYSTAL MATERIALS | MERCK PATENT GMBH (DE) | 2011-12-14 | — | — | EP | claimed |
| US-7943061-B2 | Chiral binaphthyl sulfates for use as liquid crystal materials | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-05-17 | — | — | US | claimed |
| US-20100019199-A1 | CHIRAL BINAPHTHYL SULFATES FOR USE AS LIQUID CRYSTAL MATERIALS | MERCK PATENT GESELLSCHAFT (DE) | 2010-01-28 | — | — | US | claimed |
| EP-2004622-A1 | CHIRAL BINAPHTHYL SULFATES FOR USE AS LIQUID CRYSTAL MATERIALS | Merck Patent GmbH (DE) | 2008-12-24 | — | — | EP | claimed |
| WO-2007115639-A1 | CHIRAL BINAPHTHYL SULFATES FOR USE AS LIQUID CRYSTAL MATERIALS | MERCK PATENT GMBH (DE) | 2007-10-18 | — | — | WO | claimed |
| EP-2004622-B1 | CHIRAL BINAPHTHYL SULFATES FOR USE AS LIQUID CRYSTAL MATERIALS | MERCK PATENT GMBH (DE) | 2011-12-14 | — | — | EP | disclosed |
| US-7943061-B2 | Chiral binaphthyl sulfates for use as liquid crystal materials | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-05-17 | — | — | US | disclosed |
| US-20100019199-A1 | CHIRAL BINAPHTHYL SULFATES FOR USE AS LIQUID CRYSTAL MATERIALS | MERCK PATENT GESELLSCHAFT (DE) | 2010-01-28 | — | — | US | disclosed |
| EP-2004622-A1 | CHIRAL BINAPHTHYL SULFATES FOR USE AS LIQUID CRYSTAL MATERIALS | Merck Patent GmbH (DE) | 2008-12-24 | — | — | EP | disclosed |
| WO-2007115639-A1 | CHIRAL BINAPHTHYL SULFATES FOR USE AS LIQUID CRYSTAL MATERIALS | MERCK PATENT GMBH (DE) | 2007-10-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100019199-A1 | CHIRAL BINAPHTHYL SULFATES FOR USE AS LIQUID CRYSTAL MATERIALS | DVL3, DVL1, EBPL | POLB 2308/4885CTRB1 4107/4885PTPN22 1749/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.