Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | HBB | P68871 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10614725 | 0.85 | NCOA3 (0.46) | ALDH1A1CYP3A4HSD17B10ALOX15CASP1 | |
| SCHEMBL818634 | 0.79 | CA1 (0.44) | ALDH1A1KDM4EGAACA1CA2 | |
| SCHEMBL11415340 | 0.78 | CYP2A6 (0.42) | ALDH1A1HSD17B10TDP1KDM4EGAA | |
| SCHEMBL29176655 | 0.78 | CYP1A2 (0.42) | ALDH1A1KDM4EGAACA1CA2 | |
| SCHEMBL5749904 | 0.77 | ALDH1A1 (0.55) | ALDH1A1CYP3A4HSD17B10ALOX15CASP1 | |
| SCHEMBL5749714 | 0.77 | ALDH1A1 (0.55) | ALDH1A1CYP3A4HSD17B10ALOX15CASP1 | |
| SCHEMBL31588131 | 0.76 | ESR2 (0.54) | ALDH1A1KDM4EGAACA1CA2 | |
| SCHEMBL29176673 | 0.76 | ESR2 (0.54) | ALDH1A1KDM4EGAACA1CA2 | |
| SCHEMBL32172 | 0.76 | CA1 (0.52) | ALDH1A1HSD17B10HIF1AKDM4EGAA | |
| SCHEMBL31050903 | 0.76 | CA1 (0.52) | ALDH1A1HSD17B10HIF1AKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |