Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | PLAT | P00750 | 1/20 | 0.40 |
| ▸ | KLK1 | P06870 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5749799 | 0.94 | HTT (0.44) | HTTALDH1A1CYP3A4HPGDTSHR | |
| SCHEMBL818940 | 0.88 | HTT (0.52) | HTTALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL18322219 | 0.82 | HTT (0.53) | HTTALDH1A1TSHRHSD17B10CA1 | |
| SCHEMBL29704534 | 0.82 | ALDH1A1 (0.59) | ALDH1A1CYP3A4HPGDTSHRHSD17B10 | |
| SCHEMBL2891381 | 0.82 | ALDH1A1 (0.59) | ALDH1A1CYP3A4HPGDTSHRHSD17B10 | |
| SCHEMBL31050903 | 0.80 | CA1 (0.52) | HTTALDH1A1TSHRHSD17B10CA1 | |
| SCHEMBL32172 | 0.80 | CA1 (0.52) | HTTALDH1A1TSHRHSD17B10CA1 | |
| SCHEMBL31050902 | 0.80 | CA1 (0.52) | HTTALDH1A1TSHRHSD17B10CA1 | |
| SCHEMBL28488846 | 0.79 | CA1 (0.50) | HTTALDH1A1CYP3A4TSHRHSD17B10 | |
| SCHEMBL30858824 | 0.79 | CA1 (0.50) | HTTALDH1A1CYP3A4TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |