Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 6/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5746794 | 0.84 | HTR1A (0.60) | HTR1ASMN1; SMN2 | |
| SCHEMBL5745908 | 0.82 | HTR1A (0.52) | HTR1ASMN1; SMN2ALDH1A1KDM4EMEN1 | |
| SCHEMBL4781452 | 0.81 | HTR1A (0.52) | HTR1ASMN1; SMN2ALDH1A1KDM4EMEN1 | |
| SCHEMBL4903665 | 0.78 | HTR1A (0.48) | HTR1ASMN1; SMN2ALDH1A1KDM4EMEN1 | |
| SCHEMBL4905304 | 0.77 | HTR1A (0.48) | HTR1ASMN1; SMN2ALDH1A1KDM4EMEN1 | |
| SCHEMBL5744144 | 0.77 | HTR1A (0.47) | HTR1ASMN1; SMN2ALDH1A1KDM4EMEN1 | |
| SCHEMBL4725440 | 0.76 | HTR1A (0.69) | HTR1A | |
| SCHEMBL5746121 | 0.75 | HTR1A (0.70) | HTR1A | |
| SCHEMBL4252077 | 0.74 | HTR1A (0.72) | HTR1ASMN1; SMN2 | |
| SCHEMBL4252076 | 0.74 | HTR1A (0.72) | HTR1ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1544201-B1 | NOVEL DERIVATIVES OF CYCLOALCANODIONES, METHOD FOR THE PRODUCTION THEREOF AND THEIR PHARMACOLOGICAL APPLICATIONS | CEPA SCHWARZ PHARMA S L (ES) | 2006-06-28 | — | — | EP | disclosed |
| EP-1544201-A1 | NOVEL DERIVATIVES OF CYCLOALCANODIONES, METHOD FOR THE PRODUCTION THEREOF AND THEIR PHARMACOLOGICAL APPLICATIONS | Cepa Schwarz Pharma s.l. (ES) | 2005-06-22 | — | — | EP | disclosed |