Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RHOA | P61586 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL192554 | 0.95 | ABL1 (0.49) | ABL1RIN1KMT2AALDH1A1POLB | |
| SCHEMBL193173 | 0.95 | ABL1 (0.49) | ABL1RIN1KMT2AALDH1A1POLB | |
| SCHEMBL193737 | 0.85 | GLA (0.55) | KMT2AALDH1A1POLBEPHX2SMN1; SMN2 | |
| SCHEMBL193105 | 0.85 | GLA (0.55) | KMT2AALDH1A1POLBEPHX2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL192965 | 0.84 | GLA (0.54) | KMT2AALDH1A1POLBEPHX2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL192966 | 0.84 | GLA (0.54) | KMT2AALDH1A1POLBEPHX2SMN1; SMN2 | |
| SCHEMBL192954 | 0.79 | KMT2A (0.64) | KMT2AALDH1A1POLBEPHX2MEN1 | |
| SCHEMBL4676318 | 0.76 | ALDH1A1 (0.46) | ABL1RIN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL5744176 | 0.76 | ALDH1A1 (0.46) | ABL1RIN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL27670399 | 0.75 | EPHX2 (0.54) | KMT2AALDH1A1POLBEPHX2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1685105-A1 | ALLOSTERIC MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | Addex Pharmaceuticals SA (CH) | 2006-08-02 | — | — | EP | disclosed |
| WO-2005044797-A1 | ALLOSTERIC MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | ADDEX PHARMACEUTICALS SA (CH) | 2005-05-19 | — | — | WO | disclosed |