Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.61 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.61 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20608405 | 1.00 | GPR84 (0.61) | GPR84FFAR1FFAR4CA1NFKB1 | |
| SCHEMBL21218753 | 0.98 | GPR84 (0.65) | GPR84FFAR1FFAR4MAPT | |
| SCHEMBL21218755 | 0.98 | GPR84 (0.65) | GPR84FFAR1FFAR4MAPT | |
| SCHEMBL4324869 | 0.98 | GPR84 (0.65) | GPR84FFAR1FFAR4MAPT | |
| SCHEMBL11862843 | 0.96 | GPR84 (0.63) | GPR84FFAR1FFAR4MAPT | |
| SCHEMBL20608406 | 0.93 | — | — | |
| SCHEMBL8995851 | 0.82 | — | — | |
| SCHEMBL7045666 | 0.80 | GPR84 (0.67) | GPR84FFAR1FFAR4CA1NFKB1 | |
| SCHEMBL4844023 | 0.79 | GPR84 (0.43) | GPR84FFAR1CA1MAPT | |
| SCHEMBL1785261 | 0.78 | GPR84 (0.64) | GPR84FFAR1FFAR4CA1NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012017400-A1 | SYNTHESIS OF ACYL-PANTETHEINE DERIVATIVES AND THE USE THEREOF IN THE SYNTHESIS OF ACYL-COENZYME A DERIVATIVES | NORTH-WEST UNIVERSITY (ZA) | 2012-02-09 | — | — | WO | disclosed |
| US-5340833-A | Antiarthritic, antiinflammatory, antitumor agents | EISAI CO., LTD. (JP) | 1994-08-23 | — | — | US | disclosed |
| EP-0568289-A2 | Benzothiophenes and thienothiophenes and related compounds useful, for example, as urokinase inhibitors | Eisai Co., Ltd. (JP) | 1993-11-03 | — | — | EP | disclosed |