Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | IKBKB | O14920 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | BTK | Q06187 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15703550 | 0.80 | KDM4E (0.38) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL13093697 | 0.77 | IKBKB (0.53) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL19798164 | 0.73 | PTGS1 (0.40) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL4260936 | 0.72 | IKBKB (0.59) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL5491089 | 0.70 | ALDH1A1 (0.58) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL15574621 | 0.70 | MAPT (0.40) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL27712393 | 0.70 | MAPT (0.49) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL27655295 | 0.68 | MAPT (0.49) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL6232939 | 0.67 | MAPT (0.56) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL4976048 | 0.67 | IKBKB (0.53) | MAPTALDH1A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1651631-A1 | BICYCLIC IMIDAZOL DERIVATIVES AGAINST FLAVIVIRIDAE | GENELABS TECHNOLOGIES, INC. (US) | 2006-05-03 | — | — | EP | disclosed |
| WO-2005012288-A1 | BICYCLIC IMIDAZOL DERIVATIVES AGAINST FLAVIVIRIDAE | GENELABS TECHNOLOGIES, INC (US) | 2005-02-10 | — | — | WO | disclosed |