SCHEMBL5747296

SCHEMBL5747296

Cc1cc2cccc3ccc4ccc(N)c1c4c32

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 0.45
TSHR P16473 4/20 0.45
TDP1 Q9NUW8 4/20 0.45
ALDH1A1 P00352 3/20 0.45
HPGD P15428 2/20 0.45
HSD17B10 Q99714 2/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
CYP1A2 P05177 4/20 0.44
CYP1A1 P04798 2/20 0.44
CYP1B1 Q16678 2/20 0.44
ERBB2 P04626 1/20 0.38
FYN P06241 1/20 0.38
MAOA P21397 1/20 0.38
ACHE P22303 1/20 0.38
AHR P35869 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
KDM4E B2RXH2 2/20 0.36
GLO1 Q04760 1/20 0.36
CD44 P16070 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9082223 0.81 ALDH1A1 (0.50) CYP3A4TSHRTDP1ALDH1A1HPGD
SCHEMBL5745730 0.79 ALDH1A1 (0.55) CYP3A4TSHRTDP1ALDH1A1HPGD
SCHEMBL28851018 0.76 ALDH1A1 (0.45) CYP3A4TSHRTDP1ALDH1A1HPGD
SCHEMBL5749715 0.76 KDM4E (0.41) CYP3A4TSHRTDP1ALDH1A1HPGD
SCHEMBL5745785 0.76 NPC1 (0.42) CYP3A4TSHRTDP1ALDH1A1HPGD
SCHEMBL5748513 0.76 ALDH1A1 (0.55) CYP3A4TSHRTDP1ALDH1A1HPGD
SCHEMBL5746526 0.74 ALDH1A1 (0.59) CYP3A4TSHRTDP1ALDH1A1HPGD
SCHEMBL5251202 0.73 ALDH1A1 (0.43) CYP3A4TSHRTDP1ALDH1A1HPGD
SCHEMBL5747755 0.73 ALDH1A1 (0.52) CYP3A4TSHRTDP1ALDH1A1HPGD
Hydrochloric Acid SCHEMBL28304403 0.73 ALDH1A1 (0.57) CYP3A4TSHRTDP1ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060293503-A1 Polyaminopyridines and method for producing same SUMITOMO SEIKA CHEMICALS CO., LTD (JP) 2006-12-28 US disclosed
EP-1669390-A1 POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 2006-06-14 EP disclosed