Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14429787 | 0.80 | PDE3B (0.44) | PDE3BPDE3AKCNH2MAOAMAOB | |
| SCHEMBL13062776 | 0.77 | PDE3B (0.46) | PDE3BPDE3AKCNH2MAOAMAOB | |
| SCHEMBL1267822 | 0.74 | PDE3B (0.46) | PDE3BPDE3AKCNH2MAOAMAOB | |
| SCHEMBL13356413 | 0.74 | PDE3B (0.43) | PDE3BPDE3AKCNH2MAOAMAOB | |
| SCHEMBL5659120 | 0.74 | ATM (0.50) | MAOAMAOBHPGDALDH1A1LMNA | |
| SCHEMBL5438754 | 0.74 | KCNH2 (0.43) | PDE3BPDE3AKCNH2 | |
| SCHEMBL2294784 | 0.72 | KCNH2 (0.42) | KCNH2 | |
| SCHEMBL1712099 | 0.72 | KCNH2 (0.42) | KCNH2 | |
| SCHEMBL15791766 | 0.71 | KCNH2 (0.41) | KCNH2 | |
| SCHEMBL15791859 | 0.70 | KCNH2 (0.41) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1419155-B1 | PIPERIDINE DERIVATIVES AS ANTIBACTERIAL AGENTS | SMITHKLINE BEECHAM PLC (GB) | 2006-11-08 | — | — | EP | disclosed |