SCHEMBL5747475

SCHEMBL5747475

Cc1cc2cc(N)cc3ccc4cccc1c4c32

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.55
HSD17B10 Q99714 6/20 0.55
HPGD P15428 4/20 0.55
CYP3A4 P08684 4/20 0.55
TDP1 Q9NUW8 3/20 0.55
TSHR P16473 2/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
CYP1A2 P05177 6/20 0.47
ERBB2 P04626 1/20 0.47
FYN P06241 1/20 0.47
MAOA P21397 1/20 0.47
ACHE P22303 1/20 0.47
AHR P35869 1/20 0.47
THRB P10828 1/20 0.42
CYP1A1 P04798 2/20 0.39
CYP1B1 Q16678 2/20 0.39
KDM4E B2RXH2 1/20 0.39
CYP2A6 P11509 3/20 0.37
BACE1 P56817 1/20 0.37
CCR1 P32246 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5747755 0.91 ALDH1A1 (0.52) ALDH1A1HSD17B10HPGDCYP3A4TDP1
SCHEMBL15327722 0.89 ALDH1A1 (0.68) ALDH1A1HSD17B10HPGDCYP3A4TDP1
SCHEMBL31162741 0.89 ALDH1A1 (0.68) ALDH1A1HSD17B10HPGDCYP3A4TDP1
SCHEMBL5748513 0.82 ALDH1A1 (0.55) ALDH1A1HSD17B10HPGDCYP3A4TDP1
SCHEMBL5746596 0.81 ALDH1A1 (0.63) ALDH1A1HSD17B10HPGDCYP3A4TDP1
SCHEMBL5574510 0.80 CYP3A4 (0.61) ALDH1A1HSD17B10HPGDCYP3A4TDP1
SCHEMBL24041353 0.79 TDP1 (0.46) ALDH1A1HSD17B10HPGDCYP3A4TDP1
SCHEMBL23023807 0.79 ALDH1A1 (0.61) ALDH1A1HSD17B10HPGDCYP3A4TDP1
SCHEMBL5745730 0.79 ALDH1A1 (0.55) ALDH1A1HSD17B10HPGDCYP3A4TDP1
SCHEMBL5750151 0.78 CYP1A2 (0.43) ALDH1A1HSD17B10HPGDCYP3A4TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113651859-B 4-methyl-6-phenyl-8-ferrocenyl pyranone quinoline and preparation method and application thereof 河南中烟工业有限责任公司 2023-11-21 CN claimed
CN-113651859-A 4-methyl-6-phenyl-8-ferrocenyl pyrone quinoline and preparation method and application thereof 河南中烟工业有限责任公司 2021-11-16 CN claimed
CN-113651859-B 4-methyl-6-phenyl-8-ferrocenyl pyranone quinoline and preparation method and application thereof 河南中烟工业有限责任公司 2023-11-21 CN disclosed
CN-113651859-B 4-methyl-6-phenyl-8-ferrocenyl pyranone quinoline and preparation method and application thereof 河南中烟工业有限责任公司 2023-11-21 CN disclosed
CN-113651859-A 4-methyl-6-phenyl-8-ferrocenyl pyrone quinoline and preparation method and application thereof 河南中烟工业有限责任公司 2021-11-16 CN disclosed
CN-113651859-A 4-methyl-6-phenyl-8-ferrocenyl pyrone quinoline and preparation method and application thereof 河南中烟工业有限责任公司 2021-11-16 CN disclosed
US-20060293503-A1 Polyaminopyridines and method for producing same SUMITOMO SEIKA CHEMICALS CO., LTD (JP) 2006-12-28 US disclosed
EP-1669390-A1 POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 2006-06-14 EP disclosed