Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | ESRRG | P62508 | 2/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | FURIN | P09958 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | GCGR | P47871 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12755590 | 1.00 | RAB9A (0.43) | RAB9ANPC1ESRRGAGTR1SMN1; SMN2 | |
| SCHEMBL5748671 | 0.92 | ESRRG (0.49) | RAB9ANPC1ESRRGAGTR1SMN1; SMN2 | |
| SCHEMBL12755591 | 0.91 | RAB9A (0.44) | RAB9ANPC1ESRRGAGTR1SMN1; SMN2 | |
| SCHEMBL1483459 | 0.91 | RAB9A (0.44) | RAB9ANPC1ESRRGAGTR1SMN1; SMN2 | |
| SCHEMBL1483464 | 0.91 | RAB9A (0.44) | RAB9ANPC1ESRRGAGTR1SMN1; SMN2 | |
| SCHEMBL12755649 | 0.90 | ESRRG (0.52) | RAB9ANPC1ESRRGAGTR1SMN1; SMN2 | |
| SCHEMBL12829967 | 0.89 | KMT2A (0.46) | RAB9ANPC1ESRRGAGTR1SMN1; SMN2 | |
| SCHEMBL12755585 | 0.89 | ESRRG (0.49) | RAB9ANPC1ESRRGAGTR1SMN1; SMN2 | |
| SCHEMBL12755655 | 0.88 | MTOR (0.50) | RAB9ANPC1ESRRGAGTR1SMN1; SMN2 | |
| SCHEMBL12755654 | 0.88 | RAB9A (0.45) | RAB9ANPC1ESRRGAGTR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1798739-A | 3-alkylidenehydrazino substituted heteroaryl compounds as thrombopoietin receptor activators | NISSAN CHEMICAL IND LTD (JP) | 2006-07-05 | — | — | CN | disclosed |
| EP-1636192-A1 | 3-ALKYLIDENEHYDRAZINO SUBSTITUTED HETEROARYL COMPOUNDS AS THROMBOPOIETIN RECEPTOR ACTIVATORS | Nissan Chemical Industries, Ltd. (JP) | 2006-03-22 | — | — | EP | disclosed |
| WO-2004108683-A1 | 3-ALKYLIDENEHYDRAZINO SUBSTITUTED HETEROARYL COMPOUNDS AS THROMBOPOIETIN RECEPTOR ACTIVATORS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2004-12-16 | — | — | WO | disclosed |