Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.56 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.30 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5749886 | 1.00 | CYP1A2 (0.56) | CYP1A2CYP2A6AKR1C3AKR1C2RIOK2 | |
| SCHEMBL5748073 | 0.86 | CYP1A2 (0.53) | CYP1A2CYP2A6AKR1C3AKR1C2RIOK2 | |
| SCHEMBL4950178 | 0.86 | CYP1A2 (0.53) | CYP1A2CYP2A6AKR1C3AKR1C2RIOK2 | |
| SCHEMBL2254826 | 0.84 | SIGMAR1 (0.42) | CYP1A2CYP2A6SIGMAR1BCHE | |
| SCHEMBL2256224 | 0.84 | SIGMAR1 (0.42) | CYP1A2CYP2A6SIGMAR1BCHE | |
| SCHEMBL2253863 | 0.82 | SIGMAR1 (0.40) | HTR2AHTR2CSIGMAR1ALDH1A1LMNA | |
| SCHEMBL2256254 | 0.82 | SIGMAR1 (0.40) | HTR2AHTR2CSIGMAR1ALDH1A1LMNA | |
| SCHEMBL2257127 | 0.82 | SIGMAR1 (0.40) | HTR2AHTR2CSIGMAR1ALDH1A1LMNA | |
| SCHEMBL2251999 | 0.82 | SIGMAR1 (0.40) | HTR2AHTR2CSIGMAR1ALDH1A1LMNA | |
| SCHEMBL5745654 | 0.82 | SIGMAR1 (0.40) | HTR2AHTR2CSIGMAR1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |