SCHEMBL5747779

SCHEMBL5747779

O=CCc1ccc(Oc2ccc(Cl)cc2)cc1Cl

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.40
MAOB P27338 2/20 0.40
HTR2A P28223 7/20 0.40
SLC6A4 P31645 7/20 0.40
KCNH2 Q12809 7/20 0.40
SOS1 Q07889 1/20 0.39
NR4A2 P43354 1/20 0.37
IDO1 P14902 3/20 0.36
PPARG P37231 1/20 0.35
PPARA Q07869 1/20 0.35
HSP90AA1 P07900 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28659130 0.81 HTR2A (0.50) MAOAMAOBHTR2ASLC6A4KCNH2
SCHEMBL895205 0.80 IDO1 (0.54) IDO1
SCHEMBL29439097 0.80 IDO1 (0.54) IDO1
SCHEMBL3647629 0.80 SLC6A4 (0.43) HTR2ASLC6A4KCNH2
SCHEMBL480070 0.79 SLC6A4 (0.43) HTR2ASLC6A4KCNH2IDO1MEN1
SCHEMBL6446133 0.78 MAOB (0.48) MAOAMAOBNR4A2PPARGPPARA
SCHEMBL15823881 0.77 AHR (0.45) IDO1
SCHEMBL27585018 0.77 NR4A2 (0.43) MAOAMAOBHTR2ASLC6A4KCNH2
SCHEMBL15809203 0.75 CHRM1 (0.48) NR4A2PPARGPPARA
SCHEMBL14793788 0.74 L3MBTL1 (0.44) MAOAMAOBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118108587-A Method for preparing phenylate ketone bromide 江苏扬农化工股份有限公司 2024-05-31 CN claimed
CN-100358855-C Production method of 4- (4-chlorophenoxy) -2-chlorophenyl-methyl ketone JIANGSU CHANGQING NONGHUA CO L (CN) 2008-01-02 CN claimed
CN-1493557-A Production method of 4- (4-chlorophenoxy) -2-chlorophenyl-methyl ketone 江苏长青农化股份有限公司 2004-05-05 CN claimed
CN-118108587-A Method for preparing phenylate ketone bromide 江苏扬农化工股份有限公司 2024-05-31 CN disclosed
CN-118108587-A Method for preparing phenylate ketone bromide 江苏扬农化工股份有限公司 2024-05-31 CN disclosed
US-20150351401-A1 SUBSTITUTED [1,2,4]TRIAZOLE AND IMIDAZOLE COMPOUNDS BASF SE (DE) 2015-12-10 US disclosed
EP-2935225-A1 SUBSTITUTED [1,2,4]TRIAZOLE AND IMIDAZOLE COMPOUNDS BASF SE (DE) 2015-10-28 EP disclosed
WO-2014095655-A1 SUBSTITUTED [1,2,4]TRIAZOLE AND IMIDAZOLE COMPOUNDS BASF SE (DE) 2014-06-26 WO disclosed
EP-2746260-A1 Substituted [1,2,4]triazole and imidazole compounds BASF SE (DE) 2014-06-25 EP disclosed
CN-100358855-C Production method of 4- (4-chlorophenoxy) -2-chlorophenyl-methyl ketone JIANGSU CHANGQING NONGHUA CO L (CN) 2008-01-02 CN disclosed
CN-100358855-C Production method of 4- (4-chlorophenoxy) -2-chlorophenyl-methyl ketone JIANGSU CHANGQING NONGHUA CO L (CN) 2008-01-02 CN disclosed
EP-1651631-A1 BICYCLIC IMIDAZOL DERIVATIVES AGAINST FLAVIVIRIDAE GENELABS TECHNOLOGIES, INC. (US) 2006-05-03 EP disclosed
WO-2005012288-A1 BICYCLIC IMIDAZOL DERIVATIVES AGAINST FLAVIVIRIDAE GENELABS TECHNOLOGIES, INC (US) 2005-02-10 WO disclosed
CN-1493557-A Production method of 4- (4-chlorophenoxy) -2-chlorophenyl-methyl ketone 江苏长青农化股份有限公司 2004-05-05 CN disclosed
CN-1493557-A Production method of 4- (4-chlorophenoxy) -2-chlorophenyl-methyl ketone 江苏长青农化股份有限公司 2004-05-05 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150351401-A1 SUBSTITUTED [1,2,4]TRIAZOLE AND IMIDAZOLE COMPOUNDS CYP1B1, CYP4B1, COX4I1 MAOA 224/4885MAOB 132/4885HTR2A 1473/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.