Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | VNN1 | O95497 | 7/20 | 0.44 |
| ▸ | CCNK | O75909 | 1/20 | 0.43 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.41 |
| ▸ | PDE2A | O00408 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3867897 | 1.00 | ALDH1A1 (0.45) | ALDH1A1VNN1CCNKCDK12KMT2A | |
| SCHEMBL3863247 | 0.91 | KMT2A (0.45) | ALDH1A1VNN1CCNKCDK12KMT2A | |
| SCHEMBL5746384 | 0.91 | KMT2A (0.45) | ALDH1A1VNN1CCNKCDK12KMT2A | |
| SCHEMBL3862802 | 0.90 | ALDH1A1 (0.46) | ALDH1A1VNN1CCNKCDK12KMT2A | |
| SCHEMBL5747668 | 0.90 | ALDH1A1 (0.46) | ALDH1A1VNN1CCNKCDK12KMT2A | |
| SCHEMBL5745597 | 0.88 | KDM5B (0.53) | ALDH1A1VNN1CCNKCDK12KMT2A | |
| SCHEMBL3864624 | 0.88 | KDM5B (0.53) | ALDH1A1VNN1CCNKCDK12KMT2A | |
| SCHEMBL3862788 | 0.86 | KMT2A (0.46) | ALDH1A1VNN1CCNKCDK12KMT2A | |
| SCHEMBL5746703 | 0.86 | KMT2A (0.46) | ALDH1A1VNN1CCNKCDK12KMT2A | |
| SCHEMBL5749432 | 0.85 | ALDH1A1 (0.47) | ALDH1A1VNN1CCNKCDK12KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1680415-A1 | PYRROLIDINYL UREA DERIVATIVES AS ANGIOGENESIS INHIBITORS | Abbott Laboratories (US) | 2006-07-19 | — | — | EP | disclosed |
| WO-2005035524-A1 | PYRROLIDINYL UREA DERIVATIVES AS ANGIOGENSIS INHIBITORS | ABBOTT LABORATORIES (US) | 2005-04-21 | — | — | WO | disclosed |