Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | ATM | Q13315 | 3/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5748193 | 0.90 | CYP1A2 (0.43) | PARP1ALDH1A1HPGDHSD17B10CYP1A2 | |
| SCHEMBL28943977 | 0.84 | ALDH1A1 (0.45) | ALDH1A1HPGDHSD17B10CYP1A2THRB | |
| SCHEMBL5750664 | 0.83 | CYP1A2 (0.40) | PARP1ALDH1A1HPGDHSD17B10CYP1A2 | |
| SCHEMBL27705873 | 0.82 | CYP1A2 (0.52) | ALDH1A1HPGDHSD17B10CYP1A2THRB | |
| SCHEMBL5748774 | 0.82 | TLR8 (0.46) | PARP1ALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL5751206 | 0.82 | TLR8 (0.46) | PARP1ALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL5747815 | 0.82 | TLR8 (0.46) | PARP1ALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL5749039 | 0.80 | CYP1A2 (0.43) | PARP1ALDH1A1HPGDHSD17B10CYP1A2 | |
| SCHEMBL5749079 | 0.79 | KMT2A (0.41) | PARP1ALDH1A1HPGDHSD17B10CYP1A2 | |
| SCHEMBL5747969 | 0.78 | MEN1 (0.38) | PARP1ALDH1A1HPGDHSD17B10CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |