Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 16/20 | 0.59 |
| ▸ | TLR8 | Q9NR97 | 12/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5749516 | 0.92 | TLR7 (0.54) | TLR7TLR8LMNA | |
| SCHEMBL5747394 | 0.90 | TLR7 (0.56) | TLR7TLR8LMNA | |
| SCHEMBL5748639 | 0.87 | TLR7 (0.54) | TLR7TLR8LMNA | |
| SCHEMBL5745097 | 0.86 | TLR7 (0.54) | TLR7TLR8LMNA | |
| SCHEMBL5749163 | 0.86 | TLR7 (0.53) | TLR7TLR8LMNA | |
| SCHEMBL5617011 | 0.86 | TLR7 (0.52) | TLR7TLR8LMNA | |
| SCHEMBL5748394 | 0.86 | TLR7 (0.53) | TLR7TLR8LMNA | |
| SCHEMBL5746792 | 0.84 | TLR7 (0.51) | TLR7TLR8LMNA | |
| SCHEMBL5748435 | 0.83 | TLR7 (0.49) | TLR7TLR8LMNA | |
| SCHEMBL5747228 | 0.83 | TLR7 (0.50) | TLR7TLR8LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1187613-B9 | AMIDE SUBSTITUTED IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES CO (US) | 2006-10-25 | — | — | EP | claimed |
| EP-1187613-B1 | AMIDE SUBSTITUTED IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES CO (US) | 2006-08-09 | — | — | EP | claimed |
| US-6451810-B1 | AID IN CYTOKINE BIOSYNTHESIS | 3M INNOVATIVE PROPERTIES COMPANY | 2002-09-17 | — | — | US | claimed |