Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 15/20 | 0.54 |
| ▸ | TLR8 | Q9NR97 | 11/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HRH2 | P25021 | 1/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5747394 | 0.93 | TLR7 (0.56) | TLR7TLR8POLBTHRBLMNA | |
| SCHEMBL5749163 | 0.90 | TLR7 (0.53) | TLR7TLR8POLBTHRBLMNA | |
| SCHEMBL5749516 | 0.89 | TLR7 (0.54) | TLR7TLR8POLBLMNAHRH2 | |
| SCHEMBL5745738 | 0.88 | TLR7 (0.44) | TLR7TLR8POLBTHRBLMNA | |
| SCHEMBL5746792 | 0.88 | TLR7 (0.51) | TLR7TLR8POLBTHRBLMNA | |
| SCHEMBL5748024 | 0.87 | TLR7 (0.59) | TLR7TLR8LMNA | |
| SCHEMBL5747228 | 0.87 | TLR7 (0.50) | TLR7TLR8POLBTHRBLMNA | |
| SCHEMBL5749982 | 0.86 | TLR7 (0.51) | TLR7TLR8POLBTHRBLMNA | |
| SCHEMBL5748394 | 0.86 | TLR7 (0.53) | TLR7TLR8POLBLMNAHRH2 | |
| SCHEMBL5749272 | 0.86 | TLR7 (0.49) | TLR7TLR8POLBTHRBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1187613-B9 | AMIDE SUBSTITUTED IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES CO (US) | 2006-10-25 | — | — | EP | claimed |
| EP-1187613-B1 | AMIDE SUBSTITUTED IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES CO (US) | 2006-08-09 | — | — | EP | claimed |
| US-6451810-B1 | AID IN CYTOKINE BIOSYNTHESIS | 3M INNOVATIVE PROPERTIES COMPANY | 2002-09-17 | — | — | US | claimed |