Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 6/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5749570 | 1.00 | TLR7 (0.48) | TLR7KCNH2KDM4EALDH1A1MAPT | |
| SCHEMBL5747831 | 1.00 | TLR7 (0.48) | TLR7KCNH2KDM4EALDH1A1MAPT | |
| SCHEMBL9870472 | 0.94 | TLR7 (0.41) | TLR7KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL9871357 | 0.87 | PDE10A (0.40) | TLR7KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL5748976 | 0.80 | PDE10A (0.38) | KDM4EALDH1A1MAPTHPGDRAB9A | |
| SCHEMBL3670490 | 0.72 | KCNH2 (0.42) | KCNH2KDM4EALDH1A1MAPTRAB9A | |
| SCHEMBL3670506 | 0.72 | KCNH2 (0.42) | KCNH2KDM4EALDH1A1MAPTRAB9A | |
| SCHEMBL9145259 | 0.72 | KCNH2 (0.42) | KCNH2KDM4EALDH1A1MAPTRAB9A | |
| SCHEMBL3671647 | 0.72 | KCNH2 (0.42) | KCNH2KDM4EALDH1A1MAPTRAB9A | |
| SCHEMBL2460770 | 0.72 | KCNH2 (0.42) | KCNH2KDM4EALDH1A1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |