Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
| ▸ | GABRD | O14764 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5748271 | 0.94 | TLR7 (0.48) | TLR7KDM4ENPC1ALDH1A1MAPT | |
| SCHEMBL5747831 | 0.94 | TLR7 (0.48) | TLR7KDM4ENPC1ALDH1A1MAPT | |
| SCHEMBL5749570 | 0.94 | TLR7 (0.48) | TLR7KDM4ENPC1ALDH1A1MAPT | |
| SCHEMBL9871357 | 0.90 | PDE10A (0.40) | TLR7KDM4ENPC1ALDH1A1MAPT | |
| SCHEMBL5748976 | 0.82 | PDE10A (0.38) | KDM4ENPC1ALDH1A1MAPTHPGD | |
| SCHEMBL9870873 | 0.72 | LMNA (0.38) | NPC1ALDH1A1MAPTHPGDRAB9A | |
| SCHEMBL28039436 | 0.72 | KDM4E (0.41) | KDM4EALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL7068584 | 0.70 | PDE10A (0.71) | KDM4ENPC1ALDH1A1MAPTHPGD | |
| SCHEMBL258351 | 0.70 | TLR8 (0.36) | TLR7NPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL4466341 | 0.69 | CYP1A2 (0.41) | TLR7KDM4ENPC1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1063869-A | New nitrogenous bicyclic derivatives, its preparation method, the new intermediate that obtains thus, its pharmaceutical use and the pharmaceutical composition that contains this class material | ROUSSEL UCLAF (FR) | 1992-08-26 | — | — | CN | claimed |
| CN-1063869-A | New nitrogenous bicyclic derivatives, its preparation method, the new intermediate that obtains thus, its pharmaceutical use and the pharmaceutical composition that contains this class material | ROUSSEL UCLAF (FR) | 1992-08-26 | — | — | CN | disclosed |
| US-5051447-A | Applying aromatic oximes to plants, seeds or soils | BASF AKTIENGESELLSCHAFT (DE) | 1991-09-24 | — | — | US | disclosed |