SCHEMBL5748296

SCHEMBL5748296

CCc1cc2cc[c]c3ccc4cccc1c4c32

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.37
ERBB2 P04626 1/20 0.37
FYN P06241 1/20 0.37
MAOA P21397 1/20 0.37
ACHE P22303 1/20 0.37
AHR P35869 1/20 0.37
ALDH1A1 P00352 2/20 0.35
HPGD P15428 2/20 0.35
HSD17B10 Q99714 2/20 0.35
THRB P10828 1/20 0.35
CYP3A4 P08684 1/20 0.35
TSHR P16473 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
ATM Q13315 1/20 0.35
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
NSD2 O96028 1/20 0.31
CASP6 P55212 1/20 0.31
GFER P55789 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5749129 0.91 ALDH1A1 (0.37) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL5749359 0.90 ALDH1A1 (0.36) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL5748428 0.84 KCNH2 (0.38) ALDH1A1HPGDHSD17B10CYP3A4MEN1
SCHEMBL5748721 0.84 KCNH2 (0.38) ALDH1A1HPGDHSD17B10CYP3A4MEN1
SCHEMBL5748904 0.84 KCNH2 (0.38) ALDH1A1HPGDHSD17B10CYP3A4MEN1
SCHEMBL5748614 0.83 MEN1 (0.34) ALDH1A1HPGDHSD17B10CYP3A4TSHR
SCHEMBL5746832 0.83 MEN1 (0.34) ALDH1A1HPGDHSD17B10CYP3A4TSHR
SCHEMBL27705873 0.82 CYP1A2 (0.52) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL5746674 0.80 ALDH1A1 (0.50) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL5745906 0.77 CYP1A2 (0.37) CYP1A2ERBB2FYNMAOAACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060293503-A1 Polyaminopyridines and method for producing same SUMITOMO SEIKA CHEMICALS CO., LTD (JP) 2006-12-28 US disclosed
EP-1669390-A1 POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 2006-06-14 EP disclosed