SCHEMBL5748381

SCHEMBL5748381

COCCc1nc2c(N)nc3ccccc3c2n1CCCCC1COCCN1OC(N)=O

nearest known ligand 0.57

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 20/20 0.57
TLR8 Q9NR97 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5750379 0.83 TLR7 (0.39) TLR7
SCHEMBL5616920 0.80 TLR7 (0.62) TLR7TLR8
SCHEMBL5774729 0.80 TLR7 (0.53) TLR7
SCHEMBL5616914 0.79 TLR7 (0.61) TLR7TLR8
SCHEMBL4672516 0.79 TLR7 (0.63) TLR7
SCHEMBL5747599 0.78 TLR7 (0.60) TLR7TLR8
SCHEMBL5357638 0.78 TLR7 (0.63) TLR7
SCHEMBL5617019 0.77 TLR7 (0.60) TLR7
SCHEMBL20806060 0.77 TLR7 (0.59) TLR7
SCHEMBL30851305 0.77 TLR7 (0.59) TLR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1198232-B1 UREA SUBSTITUTED IMIDAZOQUINOLINES 3M INNOVATIVE PROPERTIES CO (US) 2006-08-23 EP claimed