Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.54 |
| ▸ | PLAU | P00749 | 5/20 | 0.54 |
| ▸ | F2 | P00734 | 2/20 | 0.54 |
| ▸ | PLG | P00747 | 2/20 | 0.54 |
| ▸ | KLK1 | P06870 | 2/20 | 0.54 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.54 |
| ▸ | PLAT | P00750 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | PARP1 | P09874 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TDP2 | O95551 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.44 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5749640 | 1.00 | LCK (0.54) | LCKPLAUF2PLGKLK1 | |
| SCHEMBL6869446 | 0.87 | PTPN1 (0.54) | PLAUF2PLGKLK1PRSS1 | |
| SCHEMBL7064761 | 0.86 | PLAU (0.71) | LCKPLAUF2PLGKLK1 | |
| SCHEMBL30350858 | 0.82 | LCK (0.70) | LCKPLAUF2PLGKLK1 | |
| SCHEMBL607170 | 0.82 | LCK (0.70) | LCKPLAUF2PLGKLK1 | |
| SCHEMBL30277311 | 0.82 | LCK (0.70) | LCKPLAUF2PLGKLK1 | |
| SCHEMBL8161748 | 0.82 | LCK (0.70) | LCKPLAUF2PLGKLK1 | |
| SCHEMBL28074925 | 0.81 | LCK (0.68) | LCKPLAUF2PLGKLK1 | |
| Hydrochloric Acid SCHEMBL27922456 | 0.81 | LCK (0.68) | LCKPLAUF2PLGKLK1 | |
| SCHEMBL5008737 | 0.79 | ALDH1A1 (0.54) | PLAUF2PLGKLK1PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |